Results 271 to 280 of about 30,052 (310)

Astrocytes: Orchestrators of brain gas exchange and oxygen homeostasis

The Journal of Physiology, EarlyView.
Abstract figure legend Oxygen and carbon dioxide enter the body via breathing; in the brain astrocytes play a key role balancing oxygen delivery with carbon dioxide removal. Abstract If we consider neurons like muscles during exercise, the demand for oxygen (O2) and carbon dioxide (CO2) elimination is constantly changing.
Isabel N. Christie
wiley   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Cognitive Control and Creativity in Children: The Role of Task‐Specific Demands in Divergent Thinking

The Journal of Creative Behavior, Volume 60, Issue 1, March 2026.
ABSTRACT Cognitive control is known to support divergent thinking in adults, but findings in children remain mixed. This study examined the association between cognitive control—measured as a composite score from two executive function tasks—and verbal divergent thinking in 120 French‐speaking school‐aged children (aged 10 to 12 years). Originality and
Pier‐Luc de Chantal, Marie‐Claudelle Leblanc, Claudelle Houde‐Labrecque, Claude Labrie   +3 more
wiley   +1 more source

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Cortical spreading depression: culprits and mechanisms

Experimental Brain Research, 2022
Cortical spreading depression or CSD is an electrophysiological phenomenon affecting various perspectives of brain physiology such as ionic balance, neurotransmitter level, and blood flow in the brain. This phenomenon has greater impact on the brain function and results in the pathological contribution of many diseases in humans such as migraine with ...
Aparna Ann, Mathew, Rajitha, Panonnummal
openaire   +2 more sources

Cortical Spreading Depression in Rats

IEEE Engineering in Medicine and Biology Magazine, 2008
Cortical spreading depression (CSD) is an important neurophysiological phenomenon, which was first discovered more than 60 years ago. Optical intrinsic signal imaging (OISI) is a neuroimaging technique that can monitor a large region of the cortex with both higher temporal and spatial resolution.
Shangbin, Chen, Pengcheng, Li, Hui, Gong, Weihua, Luo, Shaoqun, Zeng, Qingming, Luo   +5 more
openaire   +2 more sources

Cortical Spreading Depression and Migraine

Current Neurology and Neuroscience Reports, 2010
Cortical spreading depression, a slowly propagating wave of transient neuronal and glial depolarization, is widely accepted as the electrophysiologic substrate of migraine aura and a trigger for headache. Recent clinical and experimental evidence reinforces the putative role of cortical spreading depression in migraine pathophysiology.
Katharina, Eikermann-Haerter, Cenk, Ayata   +1 more
openaire   +2 more sources

Cortical Spreading Depression and Estrogen

Headache: The Journal of Head and Face Pain, 2007
Cortical spreading depression (CSD) is an electrophysiological phenomenon characterized by a wave of excitation followed by inhibition. The aura phase that precedes migraine headache in about 20‐30% of migraineurs shares overlapping characteristics with CSD. Studies of rare autosomal‐dominant forms of migraine with aura provide strong evidence that the
Katharina, Eikermann-Haerter, Chiho, Kudo, Michael A, Moskowitz   +2 more
openaire   +2 more sources

Cortical spreading depression and migraine

Nature Reviews Neurology, 2013
Cortical spreading depression (CSD), a slowly propagated wave of depolarization followed by suppression of brain activity, is a remarkably complex event that involves dramatic changes in neural and vascular function. Since its original description in the 1940s, CSD has been hypothesized to be the underlying mechanism of the migraine aura.
Andrew C, Charles, Serapio M, Baca
openaire   +2 more sources

Chronic daily cortical spreading depressions suppress spreading depression susceptibility

Cephalalgia, 2011
Background: Migraine is a disabling chronic episodic disorder. Attack frequency progressively increases in some patients. Incremental cortical excitability has been implicated as a mechanism underlying progression. Cortical spreading depression (CSD) is the electrophysiological event underlying migraine aura, and a headache trigger.
Eikermann-Haerter, Katharina, Ayata, Cenk, Wang, Yumei, Qin, Tao, Dilekoz, ERGİN, Sukhotinsky, Inna, Waeber, Christian   +6 more
openaire   +3 more sources

Cortical spreading depression in migraine

Cephalalgia, 2001
Cortical spreading depression (CSD) is associated with a dramatic failure of brain ion homeostasis as well as efflux of excitatory amino acids from nerve cells and increased energy metabolism. There is strong clinical and experimental evidence to suggest that CSD is involved in the mechanism of migraine.
openaire   +3 more sources