Results 261 to 270 of about 484,106 (362)

Omission of dexamethasone in prophylaxis for highly emetogenic chemotherapy in patients with breast cancer. [PDF]

Einstein (Sao Paulo)
Rebouças CV, Alves RB, Yamada AMTD, Del Giglio A, Cruz FJSM.   +4 more
europepmc   +1 more source

In Vitro and Clinical Evaluations of UGT1A1‐, P‐gp‐, OATP1B1‐, and BCRP‐Mediated Drug–Drug Interactions of Belumosudil, a Potent ROCK2 Inhibitor

The Journal of Clinical Pharmacology, EarlyView.
Abstract Belumosudil is an oral selective rho‐associated coiled‐coil containing protein kinase 2 inhibitor, approved as a treatment for chronic graft‐versus‐host disease. Prior clinical studies demonstrated that coadministration with strong CYP3A4 inducers or proton pump inhibitors requires dose modification of belumosudil.
Olivier Schueller, Lauren Lohmer, Felix Beck, Jeegar Patel, Jasminder Sahi   +4 more
wiley   +1 more source

Severe gastrointestinal manifestations in childhood-onset lupus: A single-center cohort and review of the literature. [PDF]

Lupus
Orozco J, Nguyen J, Yasrebi SM, Blalock M, Grisales SL, Jensen CL, DeGuzman MM.   +6 more
europepmc   +1 more source

Population Pharmacokinetics and Exposure–Response Relationships of Etrolizumab in Patients with Moderately‐to‐Severely Active Crohn's Disease

The Journal of Clinical Pharmacology, EarlyView.
Abstract This study aimed to characterize the pharmacokinetics (PK) of etrolizumab, an IgG1‐humanized monoclonal anti‐β7 integrin antibody, and assess its exposure–response (ER) relationship for key clinical outcomes in patients with moderately‐to‐severely active Crohn's disease.
Anita Moein, Jakob Ribbing, Moustafa M. A. Ibrahim, Wenhui Zhang, Nastya Kassir   +4 more
wiley   +1 more source

Neurocognitive risks of asthma during childhood. [PDF]

Dev Cogn Neurosci
Christopher-Hayes NJ, Ghetti S.
europepmc   +1 more source

Home‐based collaborative management of bullous pemphigoid with delayed seropositive conversion of anti‐BP180‐NC16a antibody

Journal of General and Family Medicine, EarlyView.
We present the case of an elderly male with bullous pemphigoid, initially negative for the anti‐BP180‐NC16a antibody, which later became positive as disease activity progressed. The patient was successfully managed at home through multidisciplinary collaboration, including a general practitioner, dermatologist, nurses, and pharmacists.
Hiromitsu Yamashita, Takayuki Ando, Hirohisa Fujikawa, Masayoshi Shiota   +3 more
wiley   +1 more source

Development of a guideline for orthopaedic management in the care of children and young people with Duchenne muscular dystrophy in the UK National Health Service. [PDF]

J Child Orthop
Henman PD, Turner C, Aird J, Atherton WG, Campbell D, Carpenter C, Carsi MB, Dixon M, Giannakakis N, Girdler-Hardy T, Hulme A, James M, Joseph S, Kiely NT, Ohly K, Porter A, Rad D, Reuben E, Walton R, Wong SC, Guglieri M.   +20 more
europepmc   +1 more source

Early detection of cerebrospinal fluid/serum glucose ratio: A promising value for mortality prognosis in patients with acute bacterial meningitis

Journal of General and Family Medicine, EarlyView.
This study revealed that a glucometer‐based measurement significantly improved the turnaround time required for CSF/serum glucose ratio measurement compared to conventional laboratory tests, which could be considered a reliable aid to the mortality prognosis.
Nasrin Khodashenas, Rouzbeh Rajaei Ghafouri, Asghar Jafari Rouhi, Moloud Balafar   +3 more
wiley   +1 more source