Results 231 to 240 of about 134,745 (361)

Advancing antihypertensive drug development

British Journal of Pharmacology, Volume 182, Issue 15, Page 3389-3410, August 2025.
Hypertension affects more than a billion individuals worldwide and remains a major cause of cardiovascular morbidity and mortality. Despite advances in therapies, optimal blood pressure control remains elusive for many patients because of treatment resistance, adverse effects, and adherence challenges.
Fay Pu, Yanrong Liu, Fozia Zahir Ahmed, Xin Wang, Darren Green, Hongyuan Zhang   +5 more
wiley   +1 more source

Leptin signaling in POMC neurons regulates plasma leptin levels and is critical to mediate hypothalamic-pituitary-adrenal axis activation during fasting. [PDF]

Sci Rep
Ferreira NL, Fideles HJ, Marcal AB, Brianezi AP, Nani JVS, Mecawi AS, Rorato R.   +6 more
europepmc   +1 more source

The effects of corticosterone and cortisone on the uptake of polyvinyl pyrrolidone and the transmission of immunoglobulin G by the small intestine in young rats.

, 1976
B. Morris, R. Morris
openalex   +2 more sources

Effect of starvation or treatment with corticosterone on the amount of easily releasable myofilaments in rat skeletal muscles [PDF]

, 1986
Burkhardt Dahlmann, M Rutschmann, H. Reinauer   +2 more
openalex   +1 more source

Interplay between inflammatory reflex and energetic metabolism in endotoxaemia: A role for haem oxygenase 1?

British Journal of Pharmacology, Volume 182, Issue 16, Page 3695-3709, August 2025.
Inflammation is vital for defence against injury and infection, but excessive inflammation can lead to tissue damage and disease. The central nervous system (CNS) helps regulate immune responses through neuroendocrine pathways, such as the hypothalamic–pituitary–adrenal axis and the anti‐inflammatory reflex, which limit systemic inflammation.
Evelin C. Cárnio, Luiz G. S. Branco, Fernanda Brognara, Patrícia Passaglia, Roberta Foresti, Roberto Motterlini   +5 more
wiley   +1 more source

Effect of Corticosterone on Gene Expression in the Context of Global Hippocampal Transcription. [PDF]

Int J Mol Sci
Juszczak GR, Stankiewicz AM, Starzyński RR, Ogłuszka M, Jaszczyk A.   +4 more
europepmc   +1 more source

The Effect of Hypophysectomy upon Corticosterone-Induced Ovulation in the Hen (Gallus domesticus)

, 1979
R. J. Etches, I. Simons
openalex   +1 more source

Liquid chromatography and radioimmunoassay compared for determination of cortisol and corticosterone in plasma after a dexamethasone suppression test. [PDF]

, 1987
Kaori Oka, Makoto Noguchi, Toshinori Kitamura, Satoru Shima   +3 more
openalex   +1 more source

Osteocalcin Ameliorates CUMS‐Induced Depressive‐Like Behaviors by Reducing Mitochondrial Damage in Hippocampal Neurons

CNS Neuroscience &Therapeutics, Volume 31, Issue 8, August 2025.
After being secreted by osteoblasts, osteocalcin crosses the blood–brain barrier and interacts with GPCR receptors on hippocampal neurons. This interaction triggers a PKA‐dependent activation of the AMPK/PGC1 pathway, which, in turn, promotes the stabilization of mitochondrial function, leading to an improvement in depressive‐like behaviors in mice ...
Hui Chen, Jindong Mao, Min Wang, Qian Zhang, Rui Zheng, Zhaoxia Zhang, Qianqian Lv, Qingquan Liu, Yumei Wu, Xue Ma   +9 more
wiley   +1 more source

Epigenetic study of the long-term effects of gulf War illness. [PDF]

Front Genet
Jones BC, O'Callaghan JP, Ashbrook DG, Lu L, Prins P, Zhao W, Mozhui K.   +6 more
europepmc   +1 more source