Results 321 to 330 of about 134,745 (361)
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A Radioimmunoassay for Human Plasma Corticosterone
Endocrinologia Japonica, 1976A radioimmunoassay for human plasma corticosterone has been developed. Antiserum against corticosterone was produced in rabbits immunized with corticosterone-21-hemisuccinate conjugated to bovine serum albumin. The antiserum cross-reacted with progesterone, DOC and dehydrocorticosterone more than 20%. After the extraction with ether, and the separation
Shigeichi Matsumura +4 more
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Corticosterone and corticosterone-21-sulphate production in man
Journal of Steroid Biochemistry, 1969Abstract From isotope dilution experiments in which 3H-corticosterone-21-sulphate (B-S) or 14C-corticosterone (B) were injected intravenously into normal men and the specific activities of urinary metabolites were measured, it was estimated that 1.7–3.3 mg of B and less than 0.2 mg of B-S were secreted per day.
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Endocrinology, 1940
CORTICOSTERONE was isolated from adrenal gland extracts almost simultaneously by Kendall (i, 2) and Reichstein (3). Its chemical configuration was also eluci-dated independently by these workers (4, 5). This substance occurs in gland extracts in as great if not greater concentration than any of the other active steroids thus far obtained.
George F. Cartland, Marvin H. Kuizenga
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CORTICOSTERONE was isolated from adrenal gland extracts almost simultaneously by Kendall (i, 2) and Reichstein (3). Its chemical configuration was also eluci-dated independently by these workers (4, 5). This substance occurs in gland extracts in as great if not greater concentration than any of the other active steroids thus far obtained.
George F. Cartland, Marvin H. Kuizenga
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BINDING OF CORTICOSTERONE IN RAT LIVER
Journal of Endocrinology, 1970SUMMARY The binding characteristics of corticosterone by rat liver were studied by a displaceable binding technique. The binding of corticosterone to protein fractionated by gel filtration and density gradient centrifugation has been carried out as a preliminary determination of the nature of the binding sites.
M. K. Agarwal, N. N. Sanyal, R. S. Snart
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Corticosterone Half-Life in Children
Archives of Pediatrics & Adolescent Medicine, 1964Corticosterone (4-pregnene-11 β, 21 diol-3,20-dione; compound B) is a major product of adrenal steroidogenesis in most animal species. 1 In man, it is present in peripheral blood 2-12 and in adrenal vein effluent 3,13-15 in quantities second only to cortisol.
Alan K. Done +6 more
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Corticosterone's dual metabolic actions
Life Sciences, 1989Corticosterone possesses two distinctly opposite metabolic actions. The actions are strictly dose-dependent and are linked to type I and type II corticosteroid receptor binding. These conclusions are drawn from continuous infusion studies where corticosterone yields a bitonic dose-response curve for body weight gain and feeding efficiency.
Lynn D. Devenport +3 more
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3H-CORTICOSTERONE METABOLISM IN THE RAT
Acta Endocrinologica, 1969ABSTRACT 3H-Corticosterone was administered intravenously into two rats. After 80 min the animals were sacrificed and the radioactive material of the different tissues (intestine, liver, kidneys, lungs, adrenals, spleen and the remainder of the animal) was analyzed.
T Albepart, J Lowy, J R Pasqualini
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Rat and Mouse Brain Corticosterone
Endocrinology, 1972A procedure has been developed for determining the amount of corticosterone in mouse and rat brains. Recovery of corticosterone was shown to be between 80 and 90%. Using this procedure, values for basal levels of brain corticosterone have been obtained.
John C. Butte +2 more
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Repeatability of baseline corticosterone concentrations
General and Comparative Endocrinology, 2008One major assumption for endocrine studies is that hormone titers are consistent within an individual so that if hormone titers are low relative to the cohort on one day, they are relatively low compared to the cohort on other days. This is an especially important assumption for most field studies where researchers may have access to an individual ...
L. Michael Romero, J. Michael Reed
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Immunoanalytical characteristics of corticosterone
Immuno-analyse & Biologie Spécialisée, 2012Summary Few clinical indications of corticosterone assay exist for the assessment of adrenal pathology. However, this assay seems to be a useful index for the diagnosis of mineralcorticoid deficiency, especially in the case of aldosterone synthase deficiency.
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