Results 131 to 140 of about 515,964 (279)

Modulation of sebocyte function in acne: A pathway‐inclusive review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Acne is multifactorial, with the sebocyte acting as a central immunometabolic hub linking lipogenic, inflammatory, hormonal and barrier pathways. Mapping established and investigational therapies onto this sebocyte‐centred model offers a mechanism‐based framework that complements existing treatment paradigms and may guide more targeted, antibiotic ...
Christos C. Zouboulis, Apostolos Pappas, Katja Martin, Mauro Picardo   +3 more
wiley   +1 more source

Differential Regulation of Corticotropin-Releasing Hormone and Vasopressin Gene Transcription in the Hypothalamus by Norepinephrine

, 1999
All stress-related inputs are conveyed to the hypothalamus via several brain areas and integrated in the parvocellular division of the paraventricular nucleus (PVN) where corticotropin-releasing hormone (CRH) is synthesized. Arginine vasopressin (AVP) is
Stanley J. Watson, Manuel O. Lopez-Figueroa, Dana L. Helmreich, Keiichi Itoi   +3 more
core   +1 more source

Nature and timing of dysregulation associated with pseudoalbinism in California Halibut, Paralichthys californicus

Journal of Fish Biology, EarlyView.
Abstract Pseudoalbinism in flatfishes, the absence of melanophores or melanin over most of the ocular side of the body, is often observed in hatcheries. The prevalence of pseudoalbinism can be very high, sometimes exceeding 90% of individuals in California Halibut, Paralichthys californicus.
Lee A. Fuiman, Cynthia K. Faulk, Ruairi MacNamara   +2 more
wiley   +1 more source

Defining a serum cortisol cutoff level post-CRH stimulation for diagnosing ACTH deficiency: A retrospective study validated by a nationwide registry

Frontiers in Endocrinology
BackgroundThe corticotropin-releasing hormone (CRH) stimulation test is used to diagnose adrenocorticotropic hormone (ACTH) deficiency; however, the serum cortisol cutoff value indicating impaired response on this test (18 µg/dL [approximately 500 nmol/L]
Tetsushi Izuchi, Shintaro Iwama, Ayana Yamagami, Tomoko Kobayashi, Koji Suzuki, Takanori Murase, Masahiko Ando, Shingo Murasawa, Kosuke Mukai, Hiroshi Takagi, Hidenori Fukuoka, Tomoko Handa, Tomoko Handa, Takeshi Onoue, Takashi Miyata, Mariko Sugiyama, Daisuke Hagiwara, Hidetaka Suga, Ryoichi Banno, Ryoichi Banno, Shigeyuki Tahara, Mitsuru Nishiyama, Kazunori Kageyama, Michio Otsuki, Hiroshi Arima   +24 more
doaj   +1 more source

Identification and Treatment of Anorexia Nervosa in Women With Perimenopause

Journal of Midwifery &Women's Health, EarlyView.
Abstract Disordered eating is a common problem that midwives will encounter as frontline primary care providers. Anorexia nervosa (AN) is a form of disordered eating that results in chronic starvation state, creating significant risk of morbidity and mortality to the patient. AN is traditionally considered a disorder of adolescence and young adulthood;
Janell Senda, Sarah Carpenter, Mary Carter‐Orbke   +2 more
wiley   +1 more source

Corticotropin-releasing hormone receptors

Corticotropin-releasing hormone (CRH) and related peptides (urocortins, sauvagine, urotensin) play a central role in the co-ordination of autonomic, behavioural, cardiovascular, immune and endocrine responses to stressful stimuli.

core  

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Neuroprotection by corticotropin releasing factor during hypoxia in rat brain.

, 1993
Corticotropin releasing factor is an endogenous neuropeptide released by the hypothalamus that activates the pituitary-adrenocortical system in response to stressful stimuli.
M W Fox, F B Meyer, R E Anderson
core   +1 more source

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

Obesity Reviews, EarlyView.
ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati, David Krongauz, Alice Bosco, Antonio Noto, Cristina Piras, Maria Kafyra, Angelica Dessì, Matteo Mauri, Luigi Atzori, Adina Weinberger, Vassilios Fanos, George V. Dedoussis, on behalf of the BETTER4U consortium   +12 more
wiley   +1 more source

Of mice and men—The emerging oral–gut–brain axis of health and disease

Periodontology 2000, EarlyView.
Abstract Objectives Oral health's inextricable links to systemic health are highlighted by the emerging oral–gut–brain axis and other well‐known axes. There is growing evidence of a complex oral–gut–brain axis linking mouth and gut microbiomes with the central nervous system.
Yvonne L. Hernandez‐Kapila, Daniel J. Weisenberger   +1 more
wiley   +1 more source