Results 61 to 70 of about 80,054 (303)

Synthesis of Bioorthogonal Mycolic Acids: Chemoselective Reduction of β‐Ketoesters Containing an Alkyne Using the Noyori Catalyst

open access: yesEuropean Journal of Organic Chemistry, Accepted Article.
The asymmetric reduction of β‐ketoesters using the Noyori catalyst is a highly effective synthetic methodology, offering excellent stereocontrol for the preparation of enantiopure b‐hydroxyesters from prochiral substrates in high yields. This reaction has been used in the total synthesis of mycolic acids, which are α‐alkyl, β‐hydroxy fatty acids ...
Paulin Rollando   +5 more
wiley   +1 more source

Metabolic engineering of Corynebacterium glutamicum for anthocyanin production

open access: yesMicrobial Cell Factories, 2018
BackgroundAnthocyanins such as cyanidin 3-O-glucoside (C3G) have wide applications in industry as food colorants. Their current production heavily relies on extraction from plant tissues.
J. Zha   +7 more
semanticscholar   +1 more source

Targeting the Tumor Microbiota in Cancer Therapy Basing on Nanomaterials

open access: yesExploration, EarlyView.
Intra‐tumoral microbiota, which is a potential component of the tumor microenvironment, has been emerging as a key participant and driving factor in cancer. This article reviews the latest progress in this field, including the microbial community within tumors and its pro‐cancer mechanisms, as well as the anti‐tumor strategies targeting intra‐tumoral ...
Yanan Niu   +4 more
wiley   +1 more source

Identification and Characterization of Corynaridin, a Novel Linaridin from Corynebacterium lactis

open access: yesMicrobiology Spectrum, 2023
Genome analysis of Corynebacterium lactis revealed a bacteriocin gene cluster encoding a putative bacteriocin of the linaridin family of ribosomally synthesized and posttranslationally modified peptides (RiPPs).
Efthimia Pashou   +7 more
doaj   +1 more source

Corynebacterium ulcerans and Corynebacterium pseudotuberculosis responses to DNA probes derived from corynephage beta and Corynebacterium diphtheriae [PDF]

open access: yesInfection and Immunity, 1984
Strains of Corynebacterium ulcerans and Corynebacterium pseudotuberculosis (Corynebacterium ovis) were examined for the production of diphtheria toxin. A majority of C. ulcerans strains (25 of 37) and 1 C. pseudotuberculosis strain (1 of 14) gave a positive Elek test for diphtheria toxin, and for all strains but 1, production of diphtheria toxin was ...
J Schiller, J Russell, N Groman
openaire   +3 more sources

Corynebacterium glutamicum as platform for the production of hydroxybenzoic acids

open access: yesMicrobial Cell Factories, 2018
BackgroundHydroxybenzoic acids are industrially relevant aromatic compounds, which also play key roles in the microbial carbon metabolism, e.g., as precursors for the synthesis of cofactors or metal-chelating molecules.
Nicolai Kallscheuer, Jan Marienhagen
semanticscholar   +1 more source

Sputum Microbiota Compositions Correlate With Metabolome and Clinical Outcomes of COPD‐Bronchiectasis Association: A Prospective Cohort Study

open access: yesExploration, EarlyView.
This study aimed to determine how microbiota compositions (via 16S rRNA sequencing) correlate with clinical outcome and metabolome (via liquid chromatography/mass spectrometry) of CBA. Sputum microbiome and metabolome profiles of CBA were well separated from COPD but not bronchiectasis, partly driven by the higher abundance of Proteobacteria in CBA ...
Zhen‐feng He   +16 more
wiley   +1 more source

Corynebacterium conjunctivae: A New Corynebacterium Species Isolated from the Ocular Surface of Healthy Horses

open access: yesAnimals, 2022
Twenty-two unidentified Gram-positive, rod-shaped organisms were recovered from the conjunctival surface of apparently healthy horses and subjected to a polyphasic taxonomic analysis.
José F. Fernández-Garayzábal   +8 more
doaj   +1 more source

Corynebacterium glutamicum for Microbial Production of Chitin Oligosaccharides Using Modular Engineering

open access: yesFood Bioengineering, EarlyView.
Based on metabolic engineering, a chitin oligosaccharide (CHOSs) synthesis metabolic pathway was constructed in Corynebacterium glutamicum, establishing a cell factory for CHOSs synthesis through the selection of chassis cells and key enzymes. Utilizing this framework, multiple strategies were employed to enhance the GlcNAc and UDP‐GlcNAc synthesis ...
Chen Deng   +5 more
wiley   +1 more source

From contamination to infective endocarditis—a population-based retrospective study of Corynebacterium isolated from blood cultures

open access: yesEuropean Journal of Clinical Microbiology and Infectious Diseases, 2019
Corynebacterium is a genus that can contaminate blood cultures and also cause severe infections like infective endocarditis (IE). Our purpose was to investigate microbiological and clinical features associated with contamination and true infection.
M. Rasmussen   +2 more
semanticscholar   +1 more source

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