Results 61 to 70 of about 122,643 (306)

Synovial Fluid‐derived Micrococcus Luteus G18 Exacerbates Osteoarthritis Progression by Promoting Chondrocyte Degradation via TLR2/JNK/AP‐1 Signaling Pathway

Advanced Science, EarlyView.
Traditionally considered sterile, the articular cavity is now recognized to harbor microbial communities influencing osteoarthritis (OA). Integrating 16S rRNA sequencing and culturomics, Micrococcus luteus is enriched in advanced OA. Notably, M. luteus G18 exacerbates cartilage degeneration via TLR2/JNK/AP‐1‐mediated ECM disruption, revealing intra ...
Tingtao Chen, Qingwei Zeng, Tangchang Xu, Xinyue Qi, Kaiyi Li, Jing Wei, Liang Hao   +6 more
wiley   +1 more source

Comparing Prophylactic Administration of Sulbactam/Ampicillin Versus Cefmetazole for Prevention of Perineal Wound Infection Following Abdominoperineal Resection for Rectal Cancer: A Multicenter Randomized Controlled Trial

Annals of Gastroenterological Surgery, EarlyView.
This prospective randomized trial demonstrated that a 4‐day regimen of sulbactam/ampicillin significantly reduced the incidence of perineal wound infection (PWI) following abdominoperineal resection compared to a 1‐day cefmetazole regimen. This simple approach to antibiotic selection may be beneficial for preventing PWI.
Akitoshi Nankaku, Shunsuke Kasai, Akio Shiomi, Taiki Masuda, Hiroyuki Hazama, Noriko Iwata, Shunichiro Kato, Shinichi Yamauchi, Hiroyuki Sato, Akihiro Hirakawa, Hiroyasu Kagawa, Masanori Tokunaga, Yusuke Kinugasa   +12 more
wiley   +1 more source

Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model

Barrier Immunity, EarlyView.
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia, Mathias Hochgerner, Qingzhen Wei, Xian'ge Zhong, Jiucun Wang   +4 more
wiley   +1 more source

Effect of surgical antimicrobial prophylaxis duration for colic surgery on complications and resistome

Equine Veterinary Journal, EarlyView.
Abstract Background Based on human studies, surgical antimicrobial (AMD) prophylaxis (SAP) beyond 24 h is unnecessary and potentially detrimental. Objective To compare clinical and microbiological outcomes in patients receiving 24‐ or 72‐h of SAP for colic surgery. Study Design Prospective randomised clinical trial.
Louise L. Southwood, Alicia Long, Jairo Perez, Scott Daniel, Kyle Bittinger, Maia Aitken, Laurel Redding   +6 more
wiley   +1 more source

Identification and Characterization of Corynaridin, a Novel Linaridin from Corynebacterium lactis

Microbiology Spectrum, 2023
Genome analysis of Corynebacterium lactis revealed a bacteriocin gene cluster encoding a putative bacteriocin of the linaridin family of ribosomally synthesized and posttranslationally modified peptides (RiPPs).
Efthimia Pashou, Sebastian J. Reich, Alexander Reiter, Dominik Weixler, Bernhard J. Eikmanns, Marco Oldiges, Christian U. Riedel, Oliver Goldbeck   +7 more
doaj   +1 more source

Improving growth properties of Corynebacterium glutamicum by implementing an iron‐responsive protocatechuate biosynthesis [PDF]

, 2023
Felix Thoma, Christof Appel, Dominik Russ, Janine Huber, Felix Werner, Bastian Blombach   +5 more
openalex   +1 more source

Accelerating Enzyme Engineering With Artificial Intelligence in Biocatalysis: Challenges and Opportunities

Food Bioengineering, EarlyView.
ABSTRACT Artificial intelligence (AI) has emerged as a paradigm‐shifting force in enzyme engineering, enabling data‐driven prediction of catalytic activity, stability, and substrate specificity. By integrating large‐scale datasets from structured databases (e.g., PDB, BRENDA) and high‐throughput experimentation (e.g., deep mutational scanning ...
Xiafeng Lu, Min Cao, Muqing Ma, Yan Wu, Maohua Qu, Feng Du, Rongtao Ji, Mimi Duan, Leichi Dong, Kai Liu, Xueqi Zhang, Zhibo Luo   +11 more
wiley   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, EarlyView.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source

Retrospective evaluation of the clinical characteristics associated with Corynebacterium species bacteremia

Brazilian Journal of Infectious Diseases, 2018
Objectives: Corynebacterium spp. are becoming recognized as pathogens that potentially cause various infections. We aimed to evaluate the clinical characteristics associated with Corynebacterium spp. bacteremia.
Mitsuru Yanai, Maiko Ogasawasa, Yuta Hayashi, Kiyozumi Suzuki, Hiromichi Takahashi, Atsushi Satomura   +5 more
doaj   +1 more source

Heterologous ectoine production in Escherichia coli : By-passing the metabolic bottle-neck [PDF]

, 2008
Peer reviewedPublisher ...
Bestaver, Thorsten, Galinski, Erwin A., Louis, Petra   +2 more
core   +2 more sources