Results 71 to 80 of about 80,054 (303)

Surgical site infections and sepsis in gynecological surgery

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Despite advancements in infection control, surgical site infections (SSIs) and postoperative sepsis remain significant challenges in gynecological surgery, contributing to increased morbidity, mortality, and healthcare costs. In low‐income countries, circulatory failure due to septic shock leads to most deaths after surgery, with sepsis ...
Cristina Taliento, Gennaro Scutiero, Carmelia Milano, Mattia Grasso, Francesca Nitti, Orsola Brasile, Ruby Martinello, Giulia Bernardi, Stefano Restaino, Martina Arcieri, Matteo Pavone, Nicolò Bizzarri, Giuseppe Vizzielli, Pantaleo Greco   +13 more
wiley   +1 more source

Skin-associated Corynebacterium amycolatum shares cobamides

mSphere
The underlying interactions that occur to maintain skin microbiome composition, function, and overall skin health are largely unknown. Often, these types of interactions are mediated by microbial metabolites.
M. H. Swaney, N. Henriquez, T. Campbell, J. Handelsman, L. R. Kalan   +4 more
doaj   +1 more source

A RecET-assisted CRISPR–Cas9 genome editing in Corynebacterium glutamicum

Microbial Cell Factories, 2018
BackgroundExtensive modification of genome is an efficient manner to regulate the metabolic network for producing target metabolites or non-native products using Corynebacterium glutamicum as a cell factory.
Bo Wang, Qitiao Hu, Yu Zhang, Rui-Zhi Shi, Xin Chai, Zhe Liu, Xiuling Shang, Yun Zhang, Tingyi Wen   +8 more
semanticscholar   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

Patchoulol Production with Metabolically Engineered Corynebacterium glutamicum

Genes, 2018
Patchoulol is a sesquiterpene alcohol and an important natural product for the perfume industry. Corynebacterium glutamicum is the prominent host for the fermentative production of amino acids with an average annual production volume of ~6 million tons ...
Nadja A. Henke, Julian Wichmann, T. Baier, Jonas Frohwitter, K. Lauersen, J. Risse, P. Peters-Wendisch, O. Kruse, V. Wendisch   +8 more
semanticscholar   +1 more source

Tertiary Lymphoid Organs Are Associated With Bacterial Dysbiosis in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
Sathish Paramasivan, Ahmed Bassiouni, Nicholas A. Bokulich, Mahnaz Ramezanpour, Clare Cooksley, J. Gregory Caporasso, Shaun R. McColl, Peter‐John Wormald, Alkis J. Psaltis, Sarah Vreugde   +9 more
wiley   +1 more source

Phage‐mediated horizontal transfer of Salmonella enterica virulence genes with regulatory feedback from the host

iMeta, EarlyView.
In this study, we found evidence of phage‐mediated horizontal transfer of virulence genes in Salmonella enterica in global habitats from a molecular evolutionary perspective. Notably, csrA, a global regulator in Salmonella enterica, curbed horizontal gene transfer by inhibiting the cyclization and release of prophage.
Tianjing She, Demeng Tan, Jose Luis Balcazar, Ville‐Petri Friman, Danrui Wang, Dong Zhu, Mao Ye, Mingming Sun, Shujian Yuan, Feng Hu   +9 more
wiley   +1 more source

Clinical metagenomic analysis of bacterial communities in breast abscesses of granulomatous mastitis

International Journal of Infectious Diseases, 2016
Background: Granulomatous mastitis (GM) is a chronic inflammatory breast lesion. Its etiology remains incompletely defined. Although mounting evidence suggests the involvement of Corynebacterium in GM, there has been no systematic study of GM ...
Hai-jing Yu, Hua Deng, Jian Ma, Shu-jun Huang, Jian-min Yang, Yan-fen Huang, Xiao-ping Mu, Liang Zhang, Qi Wang   +8 more
doaj   +1 more source

Metagenomics or Metataxonomics: Best Practice Methods to Uncover the Sinus Microbiome

International Forum of Allergy &Rhinology, EarlyView.
Isabella Burdon, George Bouras, Kevin Fenix, Kenny Yeo, James Connell, Clare Cooksley, Emma Barry, Sarah Vreugde, Peter J. Wormald, Alkis J. Psaltis   +9 more
wiley   +1 more source

Synthetic biology for medical biomaterials

Interdisciplinary Medicine, EarlyView.
Synthetic biology platform has been utilized to produce a variety of medical biomaterials (MBMs), such as polylactic acid (PLA), polyhydroxyalkanoates (PHAs), hyaluronic acid (HA), collagen (COL), poly(β‐malic acid) (PMLA), poly‐γ‐glutamic acid (γ‐PGA), alginate (ALG), chitosan (CS), bacterial cellulose (BC), and antimicrobial peptides (AMPs).
Tao Xu, Xiao‐Yun Huang, Jin‐Wei Dao, Da Xiao, Dai‐Xu Wei   +4 more
wiley   +1 more source