Results 121 to 130 of about 50,525 (261)

Dissemination of antibiotic resistance genes from antibiotic producers to pathogens [PDF]

, 2017
It has been hypothesized that some antibiotic resistance genes (ARGs) found in pathogenic bacteria derive from antibiotic-producing actinobacteria. Here we provide bioinformatic and experimental evidence supporting this hypothesis.
Blin, Kai, Charusanti, Pep, Ellabaan, Mostafa M Hashim, Jiang, Xinglin, Lee, Sang Yup, Munck, Christian, Sommer, Morten Otto Alexander, Tong, Yaojun, Weber, Tilmann   +8 more
core   +1 more source

Whole-Genome Sequencing of Corynebacterium diphtheriae Isolates Recovered from an Inner-City Population Demonstrates the Predominance of a Single Molecular Strain

Journal of Clinical Microbiology, 2019
In some parts of the world, Corynebacterium diphtheriae has reemerged as a pathogen, especially as a cause of infections among impoverished and marginalized populations. We performed whole-genome sequencing (WGS) on all cutaneous C. diphtheriae isolates (
S. Chorlton, G. Ritchie, T. Lawson, M. Romney, C. Lowe   +4 more
semanticscholar   +1 more source

Innovative Wirkstoffe aus der antibakteriellen Forschung im Kampf gegen mikrobielle Resistenzen

Angewandte Chemie, Volume 137, Issue 10, March 3, 2025.
Dieser Artikel gewährt einen Überblick über in den letzten drei Jahrzehnten untersuchte antibakteriellen Wirkstoffe. Aspekte der Herkunft, der zellulären Targetstrukturen, des antibakteriellen Wirkspektrums und dem Nachweis der Wirksamkeit in Tierstudien werden zusammen mit aktuellen Entwicklungen beleuchtet.
Roderich D. Süssmuth, Marcel Kulike‐Koczula, Peng Gao, Simone Kosol   +3 more
wiley   +1 more source

Nontoxigenic Corynebacterium diphtheriae: An Emerging Pathogen in England and Wales?

Emerging Infectious Diseases, 2000
Confirmed isolates of nontoxigenic Corynebacterium diphtheriae in England and Wales increased substantially from 1986 to 1994. Ribotyping of 121 isolates confirmed in 1995 showed that 90 were of a single strain isolated exclusively from the throat; none ...
Mark Reacher, Mary Ramsay, Joanne White, Aruni De Zoysa, Androulla Efstratiou, Gina Mann, Andrew Mackay, Robert C. George   +7 more
doaj   +1 more source

Ion torrent-based transcriptional assessment of a Corynebacterium pseudotuberculosis equi strain reveals denaturing high-performance liquid chromatography a promising rRNA depletion method [PDF]

, 2013
Corynebacterium pseudotuberculosis equi is a Gram-positive pathogenic bacterium which affects a variety of hosts. Besides the great economic losses it causes to horse-breeders, this organism is also known to be an important infectious agent to cattle and
Azarani, Azarani, Baird, Barakat, Biberstein, Braverman, Bustin, Chen, Chen, Colbert, Conesa, Efstratiou, Gaspar, Hantke, Jones, Jünemann, Lukashin, Martin, Meldrum, Muto, Nguyen, Nolden, Pacheco, Papp-Wallace, Patel, Paton, Pfaffl, Piddington, Pinho, Pinto, Ramos, Ramos, Richardson, Ruiz, Sambrook, Schulz, Sorek, Spier, Swiercz, Trost, Vliet, Weinberg, Westermann, Wong, Zerbino   +44 more
core   +1 more source

Fighting Antimicrobial Resistance: Innovative Drugs in Antibacterial Research

Angewandte Chemie International Edition, Volume 64, Issue 10, March 3, 2025.
This article provides an overview over antibacterial drugs investigated in the past three decades. Aspects of the compound's origins, their cellular targets, the antibacterial spectrum and proof‐of‐concept in animal studies are covered and current trends are highlighted.
Roderich D. Süssmuth, Marcel Kulike‐Koczula, Peng Gao, Simone Kosol   +3 more
wiley   +1 more source

Corynebacterium diphtheria, Adhesion, Type and Biofilm Cultures

Эпидемиология и вакцинопрофилактика, 2019
Relevance. It is now known that toxigenic strains of Corynebacterium diphtheriae are capable not only of adhesion, but also of invasion into epithelial cells of the upper respiratory tract.
G. G. Kharseeva, A. A. Alieva, A. V. Chepusova, E. L. Alutina, O. I. Sylka   +4 more
doaj   +1 more source

Complexation of CcmB with CcmACD safeguards heme translocation for cytochrome c maturation

mLife, Volume 4, Issue 1, Page 29-44, February 2025.
Abstract Cytochrome c maturation (CCM), a posttranslational modification involving covalent attachment of heme to polypeptides (apocyt c), is essential for the activity and cellular function of cytochromes c. Here, we identify and substantiate CcmB as heme translocase in bacteria.
Yuanyou Xu, Wei Wang, Qianrou Zhang, Sirui Han, Jiahao Wang, Shihua Wu, Haichun Gao   +6 more
wiley   +1 more source

Metode Cepat Ekstraksi Dna Corynebacterium Diphtheriae Untuk Pemeriksaan Pcr [PDF]

, 2014
Diagnosis of diphtheria caused byCorynebacterium diphtheriaeshould be done immediately since delay of therapy may cause 20-fold increase rate of death. One method of rapid diagnostic to identify diphtheria is by using polymerase chain reaction (PCR). The
Fitri, N. (Nyoman), Karuniawati, A. (Anis), Malik, A. (Amarila), Muna, F. (Fauzul), Soebandrio, A. (Amin), Sunarno, S. (Sunarno)   +5 more
core   +1 more source

Electron Transport Chain Is Biochemically Linked to Pilus Assembly Required for Polymicrobial Interactions and Biofilm Formation in the Gram-Positive Actinobacterium Actinomyces oris. [PDF]

, 2017
The Gram-positive actinobacteria Actinomyces spp. are key colonizers in the development of oral biofilms due to the inherent ability of Actinomyces to adhere to receptor polysaccharides on the surface of oral streptococci and host cells.
Belkys C. Sanchez, Bryan Tran, Chenggang Wu, Chungyu Chang, Hung Ton-That, Indranil Biswas   +5 more
core   +2 more sources