Results 121 to 130 of about 49,962 (273)

Geographically Diverse Clusters of Nontoxigenic Corynebacterium diphtheriae Infection, Germany, 2016–2017

Emerging Infectious Diseases, 2018
From 2016 through the middle of 2017, the German Consiliary Laboratory on Diphtheria noted an increase in nontoxigenic Corynebacterium diphtheriae isolates submitted from cities in northern Germany.
A. Dangel, A. Berger, R. Konrad, H. Bischoff, A. Sing   +4 more
semanticscholar   +1 more source

Association Between Thyroid Hormone Levels and Disease Prognosis in Guillain–Barré Syndrome: A Retrospective Study

Health Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Introduction/Aims Guillain–Barré syndrome (GBS) is an immune‐mediated neuropathy characterized by progressive sensory and motor dysfunction, often accompanied by abnormal inflammatory markers and thyroid hormone levels. However, the underlying mechanisms and their impact on prognosis remain incompletely understood.
Yangrongzhuo Huang, Yuhan Li, Hailing Zhou, Juan Tang   +3 more
wiley   +1 more source

Corynebacterium diphtheria, Adhesion, Type and Biofilm Cultures

Эпидемиология и вакцинопрофилактика, 2019
Relevance. It is now known that toxigenic strains of Corynebacterium diphtheriae are capable not only of adhesion, but also of invasion into epithelial cells of the upper respiratory tract.
G. G. Kharseeva, A. A. Alieva, A. V. Chepusova, E. L. Alutina, O. I. Sylka   +4 more
doaj   +1 more source

Innovative Wirkstoffe aus der antibakteriellen Forschung im Kampf gegen mikrobielle Resistenzen

Angewandte Chemie, Volume 137, Issue 10, March 3, 2025.
Dieser Artikel gewährt einen Überblick über in den letzten drei Jahrzehnten untersuchte antibakteriellen Wirkstoffe. Aspekte der Herkunft, der zellulären Targetstrukturen, des antibakteriellen Wirkspektrums und dem Nachweis der Wirksamkeit in Tierstudien werden zusammen mit aktuellen Entwicklungen beleuchtet.
Roderich D. Süssmuth, Marcel Kulike‐Koczula, Peng Gao, Simone Kosol   +3 more
wiley   +1 more source

Dissemination of antibiotic resistance genes from antibiotic producers to pathogens [PDF]

, 2017
It has been hypothesized that some antibiotic resistance genes (ARGs) found in pathogenic bacteria derive from antibiotic-producing actinobacteria. Here we provide bioinformatic and experimental evidence supporting this hypothesis.
Blin, Kai, Charusanti, Pep, Ellabaan, Mostafa M Hashim, Jiang, Xinglin, Lee, Sang Yup, Munck, Christian, Sommer, Morten Otto Alexander, Tong, Yaojun, Weber, Tilmann   +8 more
core   +1 more source

Fighting Antimicrobial Resistance: Innovative Drugs in Antibacterial Research

Angewandte Chemie International Edition, Volume 64, Issue 10, March 3, 2025.
This article provides an overview over antibacterial drugs investigated in the past three decades. Aspects of the compound's origins, their cellular targets, the antibacterial spectrum and proof‐of‐concept in animal studies are covered and current trends are highlighted.
Roderich D. Süssmuth, Marcel Kulike‐Koczula, Peng Gao, Simone Kosol   +3 more
wiley   +1 more source

Complexation of CcmB with CcmACD safeguards heme translocation for cytochrome c maturation

mLife, Volume 4, Issue 1, Page 29-44, February 2025.
Abstract Cytochrome c maturation (CCM), a posttranslational modification involving covalent attachment of heme to polypeptides (apocyt c), is essential for the activity and cellular function of cytochromes c. Here, we identify and substantiate CcmB as heme translocase in bacteria.
Yuanyou Xu, Wei Wang, Qianrou Zhang, Sirui Han, Jiahao Wang, Shihua Wu, Haichun Gao   +6 more
wiley   +1 more source

PATHOGENICITY FACTORS OF CORYNEBACTERIUM NON DIPHTHERIAE

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Pathogenicity factors of Corynebacterium non diphtheriae - pili, microcapsule, cell wall, pathogenicity enzymes, toxins, that determine the ability of microorganisms to consequentially interact with epithelium of entry gates of the organism, replicate in
G. G. Kharseeva, N. A. Voronina
doaj   +1 more source

Metode Cepat Ekstraksi Dna Corynebacterium Diphtheriae Untuk Pemeriksaan Pcr [PDF]

, 2014
Diagnosis of diphtheria caused byCorynebacterium diphtheriaeshould be done immediately since delay of therapy may cause 20-fold increase rate of death. One method of rapid diagnostic to identify diphtheria is by using polymerase chain reaction (PCR). The
Fitri, N. (Nyoman), Karuniawati, A. (Anis), Malik, A. (Amarila), Muna, F. (Fauzul), Soebandrio, A. (Amin), Sunarno, S. (Sunarno)   +5 more
core   +1 more source

Insights into the flexibility of the domain‐linking loop in actinobacterial coproheme decarboxylase through structures and molecular dynamics simulations

Protein Science, Volume 34, Issue 2, February 2025.
Abstract Prokaryotic heme biosynthesis in Gram‐positive bacteria follows the coproporphyrin‐dependent heme biosynthesis pathway. The last step in this pathway is catalyzed by the enzyme coproheme decarboxylase, which oxidatively transforms two propionate groups into vinyl groups yielding heme b.
Gaurav Patil, Diego Javier Alonso de Armiño, Yirui Guo, Paul G. Furtmüller, Dominika Borek, Dario A. Estrin, Stefan Hofbauer   +6 more
wiley   +1 more source