An integrative in-silico approach for therapeutic target identification in the human pathogen Corynebacterium diphtheriae [PDF]
, 2017 Corynebacterium diphtheriae (Cd) is a Gram-positive human pathogen responsible for diphtheria infection and once regarded for high mortalities worldwide.
Azevedo, Vasco A.C. +13 more
core +10 more sources
Multilocus sequence types of invasive Corynebacterium diphtheriae isolated in the Rio de Janeiro urban area, Brazil [PDF]
, 2012 Invasive infections caused by Corynebacterium diphtheriae in vaccinated and non-vaccinated individuals have been reported increasingly. In this study we used multilocus sequence typing (MLST) to study genetic relationships between six invasive strains of
Azevedo, V. +12 more
core +1 more source
Does counseling increase sustained benefit of HAART among prison inmates after release to the community? [PDF]
, 2005 The lack of sustained effectiveness of HAART after release to the community of HIV-infected inmates treated in prison was well demonstrated by Springer et al. in a recent article.
Babudieri, Sergio +4 more
core +1 more source
Genomic analyses confirm close relatedness between Rhodococcus defluvii and Rhodococcus equi (Rhodococcus hoagii) [PDF]
, 2014 Rhodococcus defluvii strain Ca11T was isolated from a bioreactor involved in extensive phosphorus removal. We have sequenced the whole genome of this strain and our comparative genomic and phylogenetic analyses confirm its close relatedness with ...
Goodfellow, Michael +5 more
core +1 more source
Evolution of substrate specificity in a recipient's enzyme following horizontal gene transfer [PDF]
, 2013 Despite the prominent role of horizontal gene transfer (HGT) in shaping bacterial metabolism, little is known about the impact of HGT on the evolution of enzyme function.
Abascal +54 more
core +1 more source
Comparative analysis of two complete Corynebacterium ulcerans genomes and detection of candidate virulence factors [PDF]
, 2011 Background Corynebacterium ulcerans has been detected as a commensal in domestic and wild animals that may serve as reservoirs for zoonotic infections. During the last decade, the frequency and severity of human infections associated with C.
Eva Trost +19 more
core +3 more sources
Evolution, epidemiology and diversity of Corynebacterium diphtheriae : new perspectives on an old foe [PDF]
, 2016 Diphtheria is a debilitating disease caused by toxigenic Corynebacterium diphtheriae strains and has been effectively controlled by the toxoid vaccine, yet several recent outbreaks have been reported across the globe.
Hoskisson, Paul A., Sangal, Vartul
core +1 more source
Adherence and invasive properties of Corynebacterium diphtheriae strains correlates with the predicted membrane-associated and secreted proteome [PDF]
, 2015 Non-toxigenic Corynebacterium diphtheriae strains are emerging as a major cause of severe pharyngitis and tonsillitis as well as invasive diseases such as endocarditis, septic arthritis, splenic abscesses and osteomyelitis. C.
Blom, Jochen +5 more
core +2 more sources
Corynebacterium ulcerans 0102 carries the gene encoding diphtheria toxin on a prophage different from the C. diphtheriae NCTC 13129 prophage [PDF]
, 2012 BACKGROUND: Corynebacterium ulcerans can cause a diphtheria-like illness, especially when the bacterium is lysogenized with a tox gene-carrying bacteriophage that produces diphtheria toxin.
Akihiko Yamamoto +8 more
core +1 more source
Molecular epidemiology of C. diphtheriaestrains during different phases of the diphtheria epidemic in Belarus [PDF]
, 2006 Background The reemergence of epidemic diphtheria in Belarus in 1990s has provided us with important information on the biology of the disease and the diversity of the causative agent Corynebacterium diphtheriae.
Valentina Kolodkina +24 more
core +2 more sources