Results 11 to 20 of about 49,962 (273)

Outbreak of imported diphtheria with Corynebacterium diphtheriae among migrants arriving in Germany, 2022. [PDF]

Euro Surveill, 2022
From July 2022, cases of imported diphtheria with toxigenic Corynebacterium diphtheriae remarkably increased among migrants arriving in Germany. Up to 30 September 2022, 44 cases have been reported to the national public health institute, all laboratory ...
Badenschier F, Berger A, Dangel A, Sprenger A, Hobmaier B, Sievers C, Prins H, Dörre A, Wagner-Wiening C, Külper-Schiek W, Wichmann O, Sing A.   +11 more
europepmc   +3 more sources

Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae

Nature Communications, 2021
Cases of diphtheria have increased in recent years. Here, the authors analyse the genomes of 502 Corynebacterium diphtheriae isolates across 16 countries and territories over 122 years, describing an increase in antimicrobial resistance genes and ...
Robert C. Will, Thandavarayan Ramamurthy, Naresh Chand Sharma, Balaji Veeraraghavan, Lucky Sangal, Pradeep Haldar, Agila Kumari Pragasam, Karthick Vasudevan, Dhirendra Kumar, Bhabatosh Das, Eva Heinz, Vyacheslav Melnikov, Stephen Baker, Vartul Sangal, Gordon Dougan, Ankur Mutreja   +15 more
doaj   +2 more sources

Application of loop-mediated isothermal amplification combined with colorimetric and lateral flow dipstick visualization as the potential point-of-care testing for Corynebacterium diphtheriae

BMC Infectious Diseases, 2020
Background Diphtheria outbreaks occurred in endemic areas and imported and indigenous cases are reported in UE/EEA. Because of the high infectiveness and severity of the disease, early and accurate diagnosis of each suspected case is essential for the ...
Aleksandra A. Zasada, Aldona Wiatrzyk, Urszula Czajka, Klaudia Brodzik, Kamila Formińska, Ewa Mosiej, Marta Prygiel, Katarzyna Krysztopa-Grzybowska, Karol Wdowiak   +8 more
doaj   +2 more sources

Distinct Genomic Features Characterize Two Clades of Corynebacterium diphtheriae: Proposal of Corynebacterium diphtheriae Subsp. diphtheriae Subsp. nov. and Corynebacterium diphtheriae Subsp. lausannense Subsp. nov.

Frontiers in Microbiology, 2018
Corynebacterium diphtheriae is the etiological agent of diphtheria, a disease caused by the presence of the diphtheria toxin. However, an increasing number of records report non-toxigenic C. diphtheriae infections. Here, a C.
Florian Tagini, Trestan Pillonel, Antony Croxatto, Claire Bertelli, Angela Koutsokera, Alban Lovis, Gilbert Greub, Gilbert Greub   +7 more
doaj   +2 more sources

Genomic analysis of an outbreak of toxin gene bearing Corynebacterium diphtheriae in Northern Queensland, Australia reveals high level of genetic similarity. [PDF]

Epidemiol Infect, 2023
Graham RMA, Rathnayake IU, Sandhu S, Bhandari M, Taunton C, Fisher V, Hempenstall A, Marquardt T, Jennison AV.   +8 more
europepmc   +3 more sources

Beyond diphtheria toxin: cytotoxic proteins of Corynebacterium ulcerans and Corynebacterium diphtheriae

Microbiology, 2019
Diphtheria toxin is one of the best investigated bacterial toxins and the major virulence factor of toxigenic Corynebacterium diphtheriae and Corynebacterium ulcerans strains. However, also diphtheria toxin-free strains of these two species can cause severe infections in animals and humans, indicating the presence of additional virulence factors.
Dulanthi Weerasekera, Jens Möller, Max Edmund Kraner, Camila Azevedo Antunes, Ana Luiza Mattos-Guaraldi, Andreas Burkovski   +5 more
openaire   +3 more sources

Imported Toxigenic Corynebacterium Diphtheriae in Refugees with Polymicrobial Skin Infections, Germany, 2022. [PDF]

Emerg Infect Dis, 2023
During August–December 2022, toxigenic Corynebacterium diphtheriae was isolated from 25 refugees with skin infections and 2 refugees with asymptomatic throat colonization at a refugee reception center in Germany. None had systemic toxin-mediated illness.
Spielberger BD, Hansel A, Nazary A, Kleißle EM, Lehr CG, Utz M, Hofer J, Rieg S, Kern WV.   +8 more
europepmc   +2 more sources

Outbreak of Corynebacterium diphtheriae among asylum seekers in Belgium in 2022: operational challenges and lessons learnt. [PDF]

Euro Surveill, 2023
Since 2022, European countries have been facing an outbreak of mainly cutaneous diphtheria caused by toxigenic Corynebacterium diphtheriae among asylum seekers. In Belgium, between 1 March and 31 December 2022, 25 cases of toxigenic C.
Jacquinet S, Martini H, Mangion JP, Neusy S, Detollenaere A, Hammami N, Bruggeman L, Hoorelbeke B, Pierard D, Cornelissen L.   +9 more
europepmc   +2 more sources

Microbe profile : Corynebacterium diphtheriae - an old foe always ready to seize opportunity [PDF]

Microbiology, 2018
Diphtheria AB toxin mode of action. The diphtheria AB exotoxin consists of two polypeptide chains - A and B which are linked by a disulfide bridge. The B chain binds to the heparin-binding epidermal growth factor precursor on eukaryotic cells and is ...
Hoskisson, Paul A.
core   +2 more sources

Corynebacterium Diphtheriae

The Biomedical & Life Sciences Collection
Chaudhary A, Pandey S.
europepmc   +3 more sources