Results 131 to 140 of about 55,347 (258)

Synthesis of Amines for Active Pharmaceutical Ingredients Using the Whole‐Cell Factory Saccharomyces Cerevisae

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review highlights advances in engineering Saccharomyces cerevisiae for the sustainable biocatalytic production of pharmaceutically relevant amines, amino alcohols, amino acids, and complex alkaloids. It focuses on strategies to increase productivity, including enhanced enzyme expression, cofactor regeneration, precursor channeling, pathway ...
Natalia Kwiatos, Stephen Ossel, Francesco G. Mutti   +2 more
wiley   +1 more source

Gut Microbiota Alterations in Myelodysplastic Neoplasms Are Associated With Immune Dysfunction and the Therapeutic Mechanism of Hypomethylating Agents

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Myelodysplastic neoplasms (MDS) represent a group of heterogeneous clonal disorders characterized by immune dysregulation in their pathogenesis. Gut microbiota dysbiosis plays a critical role in immune modulation. Methods We collected the fecal samples of 23 newly diagnosed MDS, 10 hypomethylating agents (HMA) treated MDS and 13 age
Zhongxun Shi, Fei Huang, Chengrong Luo, Lu Yang, Yu Chen, Chun Qiao, Rong Wang, Yan Wang, Yining Yan, Linlin Wang, Lei Fan, Wenyi Shen   +11 more
wiley   +1 more source

Staphylococcus aureus and Staphylococcus lugdunensis Act in Concert to Disrupt the Nasal Epithelial Barrier

Clinical and Translational Allergy, Volume 16, Issue 5, May 2026.
ABSTRACT Introduction Chronic rhinosinusitis (CRS) pathophysiology and its link to microbiome is an area of ongoing investigation. Certain pathogens, in particular Staphylococcus aureus described to contribute to recalcitrant CRS. In addition, different species of coagulase negative staphylococci (CoNS) are frequently isolated from the sinonasal cavity
Sintayehu Ambachew, Mahnaz Ramezanpour, Clare M. Cooksley, Gohar Shaghayegh, Isabella Burdon, Emma F. Barry, Kevin Aaron Fenix, P. J. Wormald, Alkis J. Psaltis, Sarah Vreugde   +9 more
wiley   +1 more source

Fatal case of bacteremia caused by an atypical strain of Corynebacterium mucifaciens

Brazilian Journal of Infectious Diseases
Corynebacterium species have often been considered normal skin flora or contaminants; however, in recent years they have been increasingly implicated in serious infections.
Vlademir Vicente Cantarelli, Teresa Cristina. Z. Brodt, Carina Secchi, Everton Inamine, Fabiana de Souza Pereira, Diogo Andre Pilger   +5 more
doaj   +1 more source

Fungal Polysaccharides as Next‐Generation Bioactive: Advances in Structure–Activity Mapping, Mode of Action, and Biotechnological Horizons

Food Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Fungal polysaccharides (FPs) represent a diverse class of bioactive macromolecules widely studied for their nutritional, therapeutic, and biotechnological value. This review synthesizes recent advances (2020–2025) in the structural characterization, biological functions, and translational potential of FPs.
Muhammad Aaqil, Feng Zhang, Jingchuan Zheng, Muhammad Kamil, Yuwei Guo, Cunchao Zhao, Yang Tian   +6 more
wiley   +1 more source

Ultra‐Micro Powder From Edible Plants (Pueraria lobata, Cornus officinalis, Cistanche deserticola, and Dendrobium officinale) Reshapes Intestinal Flora and Attenuates Liver Injury in Alcohol‐Induced Mice

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Ultra‐micro powder from edible plants (Pueraria lobata, Cornus officinalis, Cistanche deserticola, and Dendrobium officinale) attenuates alcoholic liver injury by regulating the gut‐liver axis. It primarily reshapes the intestinal microbiota by restoring beneficial Lactobacillus populations and suppressing pathogenic bacteria like Proteobacteria and ...
Jia‐Yu Huang, Wei‐Feng Huang, Xin‐Yu Wang, Jie Cheng, Guang‐Hui Xu, Li‐Tao Yi   +5 more
wiley   +1 more source

Rare human skin infection with Corynebacterium ulcerans: transmission by a domestic cat [PDF]

, 2018
Corynebacterium ulcerans is mainly known for its ability to cause animal infections. Some strains of C. ulcerans produce diphtheria toxin, which can cause life-threatening cardiopathies and neuropathies in humans. Human cutaneous C. ulcerans infection is
Bloemberg, G., Borelli, S., Corti, M., Eich, G., Hoelzle, L., Kutzner, H., Lautenschlager, S.   +6 more
core  

Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies

MedComm, Volume 7, Issue 5, May 2026.
Tumors are no longer viewed as sterile but dynamic ecosystems harboring low‐biomass intratumoral microbiota. These microbes, derived from gut, oral cavity, or circulation, shape tumorigenesis and therapy response via core mechanisms: immunomodulation (regulating T cells, macrophages), metabolic reprogramming (SCFAs, indoles, bile acids), chronic ...
Haoling Zhang, Zengkan Du, Ping Lu, Aimin Jiang, Yadong Guo, Yawei Liu, Zhijing Song, Bing Dai, Wangzheqi Zhang   +8 more
wiley   +1 more source

The Role of Scientific Discovery in the Establishment of the First Biological Weapons Programmes [PDF]

, 2005
YesThis report addresses the scientific and technological discoveries in the biological sciences that enabled the early interest in biological warfare to move from hurling infected corpses into enemy cities in ancient times, through use of small cultures
Davison, N.
core  

A Mass Spectrometric Approach: VOC Emissions, Fatty Acid Profile, and Bacteriota Identification of Spider Communities

ChemistrySelect, Volume 11, Issue 17, 5 May 2026.
ABSTRACT This study presents the first integrated analysis of volatile organic compounds (VOCs), fatty acids, and cultivable bacteriota in whole‐body spider specimens, combining HS‐SPME‐GC/MS, GC/MS, and MALDI‐TOF‐MS. A total of 100 spiders from five synanthropic species, Steatoda opiliones, S. bipunctata, S.
Stefania Garzoli, Ján Kollár, Miroslava Kačániová   +2 more
wiley   +1 more source