Results 291 to 300 of about 8,710 (316)

Chemo‐Enzymatic Synthesis of Mixed Docosahexaenoic Acid Phosphatidylcholine Conjugates

open access: yesEuropean Journal of Organic Chemistry, Volume 28, Issue 17, May 21, 2025.
An efficient chemo‐enzymatic synthesis method is proposed for the production of mixed DHA (Docosahexaenoic acid) phosphatidylcholines, allowing access to both regioisomers with DHA positioned at either the sn1 or sn2 site. Regioisomers of acetate derivatives (AceDoPC®, DoAcePC, stabilized forms of LPC‐DHA) and phenolic‐DHA‐PCs (antioxidant drugs) were ...
Jordan Lehoux   +6 more
wiley   +1 more source

[natY/90Y]Yttrium and [natLu/177Lu]Lutetium Complexation by Rigid H4OCTAPA Derivatives. Effect of Ligand Topology

open access: yesChemistry – A European Journal, Volume 31, Issue 28, May 19, 2025.
The nature of the central spacer and the topology of the chelator plays a crucial role in the stability of [90Y]Y3+ and [177Lu]Lu3+ OCTAPA derivatives relevant for radiopharmaceutical applications. We present a detailed investigation on the coordination chemistry of [nat/90Y]Y3+ and [nat/177Lu]Lu3+ with the new acyclic chelator H4CHXOITAPA.
Fátima Lucio‐Martínez   +7 more
wiley   +1 more source

Immunological and Toxicological Assessment of Triterpenoid Saponins Bearing Lewis‐X‐ and QS‐21‐Based Trisaccharides

open access: yesChemistry – A European Journal, Volume 31, Issue 28, May 19, 2025.
The synthesis of betulinic acid and echinocystic acid saponins featuring QS‐21 minimal immunogenic motif is reported. These chimeric saponins, together with previously synthesized Lewis‐X‐containing triterpenoid saponins and a rhamnose‐modified saponin, were assessed for their toxicological and immunological profiles in wild‐type and/or hDC‐SIGN ...
Oscar Javier Gamboa Marin   +9 more
wiley   +1 more source

Synthetic Lignin Oligomers: Analytical Techniques, Challenges, and Opportunities

open access: yesChemSusChem, Volume 18, Issue 10, May 19, 2025.
The review begins by discussing lignin and its structural complexity, followed by challenges in elucidating depolymerization products and the analytical techniques used. It then focuses on the chemical structure of synthetic lignin oligomers, their synthesis mechanisms, and their significance in current science. Finally, scientific gaps are identified,
Myriam Rojas   +4 more
wiley   +1 more source

Increased oxidative stress in shoe industry workers with low-level exposure to a mixture of volatile organic compounds. [PDF]

open access: yesArh Hig Rada Toksikol
Umićević N   +8 more
europepmc   +1 more source

Knowledge of the Culture of Safety in Cholecystectomy (COSIC) Among Surgical Residents: Do We Train Them Well For Future Practice?

World Journal of Surgery, 2021
AbstractBackgroundBiliary injury is the most feared complication of laparoscopic cholecystectomy (LC). This study aimed to assess the awareness of culture of safety in cholecystectomy (COSIC) concept among the surgical residents in India.MethodsA manual survey was conducted among general surgery residents attending a postgraduate course.
Rajdeep Singh   +4 more
openaire   +2 more sources

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