Results 201 to 210 of about 27,472 (259)

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

Advanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan, Zhimeng Tang, Yanyu Luo, Bin Liu, Xinxin Huang, Jun Wei, Feng Yue   +6 more
wiley   +1 more source

Exploring variation in research priorities generated by AI tools. [PDF]

J Glob Health
Garry J, Tomlinson M, Lohan M.
europepmc   +1 more source

Photon‐Sphere Modes in Curved Optical Microcavities: A Black‐Hole Analogue Laser

Advanced Science, EarlyView.
An optical analogue of a Schwarzschild black hole is realized using curved microcavities that preserve light‐like geodesics. A new family of laser modes confined around the photon sphere is identified alongside conventional whispering‐gallery modes. Analytical theory, numerical simulations, and experiments reveal curvature‐induced confinement, enabling
Chenni Xu, Aswathy Sundaresan, Nazire‐Begüm Kazkal, Clement Lafargue, Lior Zarfaty, Li‐Gang Wang, Ofek Birnholtz, Dominique Decanini, Melanie Lebental, Patrick Sebbah   +9 more
wiley   +1 more source

Large scale compound selection guided by cell painting reveals activity cliffs and functional relationships. [PDF]

Commun Biol
Sanchez M, Bourriez N, Bendidi I, Cohen E, Svatko I, Del Nery E, Tajmouati H, Bollot G, Calzone L, Genovesio A.   +9 more
europepmc   +1 more source

Dead Matter, Living Machines: Repurposing Crustaceans' Abdomen Exoskeleton for Bio‐Hybrid Robots

Advanced Science, EarlyView.
Crustacean exoskeletons, repurposed from food waste, are engineered into sustainable bending actuators combining biotic structure with synthetic control. The augmented exoskeletons achieve rapid and robust motion with lightweight body and can be used as part of robotic manipulators, grippers and swimmers.
Sareum Kim, Kieran Gilday, Josie Hughes
wiley   +1 more source

Local Neuronal Ensembles That Coreactivate across Regions during Sleep Are Preferentially Stabilized. [PDF]

J Neurosci
Miyawaki H, Mizuseki K.
europepmc   +1 more source

Federated knowledge retrieval elevates large language model performance on biomedical benchmarks. [PDF]

Gigascience
Joy J, Su AI.
europepmc   +1 more source

Quantitative Kernel estimation from traffic signs using slanted edge spatial frequency response as a sharpness metric. [PDF]

Sci Rep
Pandey A, Akhtar MZ, Veettil NK, Wunderle B, Elger G.   +4 more
europepmc   +1 more source

Semantic Representations Are Updated Across the Lifespan Reflecting Diachronic Language Change. [PDF]

Open Mind (Camb)
Cain E, Ryskin R.
europepmc   +1 more source

StarSignDNA: mutation-to-signature attribution for accurate representation of mutational processes in low-mutation contexts. [PDF]

NAR Genom Bioinform
Bope CD, Kalyanasundaram S, Rand KD, Nakken S, Lingjærde OC, Hovig E.   +5 more
europepmc   +1 more source