Results 31 to 40 of about 64,617 (246)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

The role of specialized pro-resolving mediators in skin inflammation

Pifu-xingbing zhenliaoxue zazhi
Specialized pro-resolving mediators (SPMs) are endogenous lipid molecules that are biosynthesized from ω-3/ω-6 polyunsaturated fatty acids via key enzymes such as lipoxygenases and cyclooxygenases.
WANG Yuying, LIN Simin, WANG Xiaoying, WEI Yun, WANG Fuming, XIAO Yue, HUANG Hu, WANG Jing   +7 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Research progress on the correlation between squalene and acne vulgaris

Pifu-xingbing zhenliaoxue zazhi
Acne vulgaris is a common inflammatory skin disease involving the pilosebaceous unit. Squalene in sebum serves as a key mediator in the pathogenesis of acne.
WEI Yun, LIN Jiaxin, WANG Yuying, ZHOU Li, WANG Jing, HUANG Hu   +5 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Dual-targeting antioxidant and anti-glycation strategy inhibits melanogenesis through clinical and mechanistic study

Scientific Reports
Hyperpigmentation constitutes a significant dermatological challenge, exacerbated by oxidative stress and glycation. This study aims to develop and evaluate a novel dual-effect composition (DEC) that integrates antioxidant agents (ergothioneine and ...
Ying Ye, Jian Mu, Simin Lin, Tiantian Zhang, Fang Ye, Yuying Wang, Lingling Xuan, Changchang Chen, Panpan Yang, Jing Wang, Hu Huang   +10 more
doaj   +1 more source

Skin-whitening effect of Haematococcus pluvialis extract and its synergy with niacinamide

Journal of Dermatologic Science and Cosmetic Technology
Background: Dysregulation of melanin metabolism is a primary cause of skin hyperpigmentation, making the regulation of melanin synthesis and transfer a key focus in skin-whitening research.
Yanhong Wu, Yinli Wang, Hongbin Huang, Fan Wu, Jian Zhao, Yuanyuan Zhu, Wanting Lai, Qianqi Yu   +7 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Upcycled cosmetic ingredients: extraction process optimization via green solvents by the means of I-optimal and Box–Behnken designs

Discover Applied Sciences
Current trends are shifting attention to the sustainable valorization of food bio-waste management and by-product utilization, as they are rich in nutrients and bioactive compounds, such as dietary fiber, polyphenols, and peptides.
Nariman Ali Abdelrahim, Marina Noshy Saad, Martina Ashraf Zaghloul, Ossama Samueal Neaz   +3 more
doaj   +1 more source

Bacillus subtilis JNUCC Isolated from Galchisokjeot: Draft Genome Sequence and α-glucosidase and Tyrosinase Inhibitory Activities

Journal of Pure and Applied Microbiology, 2020
Bacterial strains isolated from fermented foods are gaining significance as they are reported to have antibacterial, antioxidant, and anticancer properties.
Hoo-Dhon Byun, Su Bin Hyun, Sungmin Bae, Ji-Min Han, Chang-Gu Hyun   +4 more
doaj   +1 more source