Results 131 to 140 of about 21,650,361 (340)

Cosmic Microwave Background, Accelerating Universe and Inhomogeneous Cosmology

open access: yes, 2005
We consider a cosmology in which a spherically symmetric large scale inhomogeneous enhancement or a void are described by an inhomogeneous metric and Einstein's gravitational equations.
Barausse E Matarrese S Riotto A   +50 more
core   +1 more source

Cohesins: Crossroad Between Cornelia de Lange Spectrum and Cancer Predisposition

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The cohesin complex plays crucial roles in DNA repair, chromatid separation, and gene transcription regulation. Pathogenic variants in cohesins or dysfunctional transcriptional regulators lead to cohesinopathies, a broader group of disorders including Cornelia de Lange Spectrum (CdLSp), for which the prevalence of cancer cases remains unclear.
Laura Rigotti   +11 more
wiley   +1 more source

Satellite Navigation for the Age of Autonomy

open access: yes, 2020
Global Navigation Satellite Systems (GNSS) brought navigation to the masses. Coupled with smartphones, the blue dot in the palm of our hands has forever changed the way we interact with the world.
Chan, Bryan   +8 more
core   +1 more source

Kampo medicines, Rokumigan, Hachimijiogan, and Goshajinkigan, significantly inhibit glucagon-induced CREB activation

open access: yesHeliyon, 2020
The pathophysiology of type 2 diabetes mellitus (T2DM) is characterized by not only insulin resistance, but also the abnormal regulation of glucagon secretion, suggesting that antagonizing the glucagon-induced signaling pathway has therapeutic potential ...
Megumi Funakoshi-Tago   +4 more
doaj  

Assessment of Radio Occultation Observations from the COSMIC-2 Mission with a Simplified Observing System Simulation Experiment Configuration

open access: yes, 2017
The mainstay of the global radio occultation (RO) system, the COSMIC constellation of six satellites launched in April 2006, is already past the end of its nominal lifetime and the number of soundings is rapidly declining because the constellation is ...
L. Cucurull, R. Li, T. R. Peevey
semanticscholar   +1 more source

Spaces with a $\mathbb{Q}$-diagonal

open access: yes, 2018
A space $X$ has a $\mathbb{Q}$-diagonal if $X^2\setminus \Delta$ has a $\mathcal{K}(\mathbb{Q})$-directed compact cover. We show that any compact space with a $\mathbb{Q}$-diagonal is metrizable, hence any Tychonorff space with a $\mathbb{Q}$-diagonal is
Feng, Ziqin
core   +1 more source

Genomics Review of Selective RET Inhibitors Sensitivity in Thyroid Cancer Clinical Trials

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT RET gene is a driver of thyroid cancer (TC) tumorigenesis. The incidence of TC has increased worldwide in the last few decades, both in medullary and follicular‐derived subtypes. Several drugs, including multikinase and selective inhibitors, have been explored.
Sara Gil‐Bernabé   +5 more
wiley   +1 more source

Development of non‐destructive analytical strategies based on Raman spectroscopy and complementary techniques for Mars Sample Return tested on Northwest Africa 1950 Martian meteorite

open access: yesJournal of Raman Spectroscopy, Volume 53, Issue 12, Page 2068-2085, December 2022., 2022
A non‐destructive analytical methodology, based on Raman microscopy (single point and imaging), micro‐energy dispersive X‐ray fluorescence (μED‐XRF) imaging analysis, and scanning electron microscopy coupled to energy dispersive spectroscopy (SEM‐EDS), is suggested for a first analytical characterization for the Martian samples that will be taken to ...
Leire Coloma   +7 more
wiley   +1 more source

Naked Forward Shock Seen in the TeV Afterglow Data of GRB 221009A

open access: yesThe Astrophysical Journal
We explore the implications of the light curve of the early TeV gamma-ray afterglow of GRB 221009A reported by the LHAASO Collaboration. We show that the reported offset of the reference time, T _* , allows the determination of the activation time of the
Dmitry Khangulyan   +2 more
doaj   +1 more source

Updated model of cosmic-ray-induced ionization in the atmosphere (CRAC:CRII_v3): Improved yield function and lookup tables

open access: yesJournal of Space Weather and Space Climate
Cosmic rays, including galactic cosmic rays and solar energetic particles, form the main source of ionization of the low and middle atmosphere, which is important for various chemical and physical effects in the atmosphere.
Usoskin I.G.   +2 more
doaj   +1 more source

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