Cancer Science, EarlyView.In hepatocellular carcinoma, the 8q24.3 locus is frequently amplified and is associated with tumor‐specific overexpression of TONSL. TONSL promotes homologous recombination repair through RAD51, limits γH2AX accumulation and apoptosis, supports tumor growth, and its loss increases sensitivity to poly (ADP‐ribose) polymerase (PARP) inhibition.
Akinori Tsujimoto +16 more
wiley +1 more source
An exploration of the structure and understanding of <i>Xin</i> ("") in Chinese culture: the development of a theoretical model and questionnaire instruments. [PDF]
Front PsycholLin L, Jing D, Sun C.
europepmc +1 more source
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are widely used for managing Type 2 diabetes and obesity, with well‐documented and significant cardiometabolic benefits. Recent observational reports and pharmacovigilance data have raised concerns about a possible association between GLP‐1RAs‐particularly semaglutide‐ and non‐arteritic ...
Helen V. Danesh‐Meyer +1 more
wiley +1 more source
Increased and varied radiation during the Sun's encounters with cold clouds in the last 10 million years. [PDF]
Sci RepOpher M +9 more
europepmc +1 more source
Cristiano of Arabia: Did Ronaldo increase Saudi Pro League attendances?
Contemporary Economic Policy, Volume 43, Issue 2, Page 260-270, April 2025.Abstract In December 2022, Cristiano Ronaldo, five‐time Ballon d’Or winner and the most‐followed person on Instagram, signed for Al‐Nassr in the Kingdom of Saudi Arabia. This marked one of several expensive, recent interventions by the kingdom in global sports markets. We exploit the timing of this event to estimate superstar effects.
Dominik Schreyer, Carl Singleton
wiley +1 more source
Synonymous and non-synonymous variants at splice junctions can disrupt splicing and are frequently linked to disease associated loss of function genes. [PDF]
BMC GenomicsSrinivasan S +6 more
europepmc +1 more source
Curating the Unexpected: Stéphane Thidet's “Weeping Stones” Transformed During COVID‐19
Curator: The Museum Journal, EarlyView.ABSTRACT A monumental work by French artist Stéphane Thidet became the nexus for an unexpected interaction between an art installation and wildlife. “Weeping Stones,” which presents a desert‐like world, devoid of greenery, was featured in an exhibition we co‐curated at the Genia Schreiber University Gallery, Tel Aviv, Israel, in January 2020.
Tamar Mayer +3 more
wiley +1 more source
Ecologization Is Not a Metaphor: Museums in the Web of Life
Curator: The Museum Journal, EarlyView.ABSTRACT This article documents and critiques emerging accounts of museum “ecologization”. Drawing on political ecology, materialist theory, and contemporary museum practice, we challenge dominant frameworks of ecological modernization and advocate for a more critical understanding of museums in the web of life.
Colin Sterling +2 more
wiley +1 more source
SigRescueR: a pan-system framework for noise correction and mutational signature identification across sequencing platforms. [PDF]
Brief BioinformNguyen PT, Zhivagui M.
europepmc +1 more source
1166. Helianthus occidentalis Riddell
Curtis's Botanical Magazine, EarlyView.Summary Helianthus occidentalis Riddell (Compositae: Heliantheae: Helianthinae) is described and illustrated. The species' placement in the genus is commented on, as are the differences in infrageneric placement of the other species Heiser originally grouped H. occidentalis with.
Nicholas Hind, Christabel King
wiley +1 more source