Results 291 to 300 of about 21,650,361 (340)

Comparative genomic analysis unveiling the mutational landscape associated with premalignant lesions and early-stage gastric cardia cancer. [PDF]

Medicine (Baltimore)
Wang G, Liu L, Zhao Y, Lin Y, Er L.
europepmc   +1 more source

Impact of Minimal Residual Disease on Early Recurrence of Liver Metastatic Colorectal Cancer

Cancer Science, EarlyView.
Our study highlights the significant role of minimal residual desease(MRD) assessment in patients with reseble CRLM, particularly in predicting early recurrence and guiding treatement decisions, suggesting that adjuvant chemotherapy may not offer substantial benefits for MRD‐negative patients.
Mampei Kawashima, Takeshi Yamada, Toshimitsu Miyasaka, Shintaro Kanaka, Sho Kuriyama, Kay Uehara, Akihisa Matsuda, Ryo Ohta, Hiromichi Sonoda, Nobuhiko Taniai, Hiroshi Yoshida   +10 more
wiley   +1 more source

Genomic landscape of gallbladder cancer: insights from whole exome sequencing. [PDF]

Int J Surg
Awasthi S, Kumar R, Pradhan D, Rawal N, Goel H, Sahu P, Sisodiya S, Rana R, Kumar S, Dash NR, Das P, Agrawal U, Rath GK, Kaur T, Dhaliwal RS, Hussain S, Saluja SS, Tanwar P.   +17 more
europepmc   +1 more source

ABSTRACTS

Precision Radiation Oncology, EarlyView.
wiley   +1 more source

Insights From Nonsense‐Mediated mRNA Decay for Prognosis in Homologous Recombination‐Deficient Ovarian Cancer

Cancer Science, EarlyView.
In this study, an NMD prediction algorithm and an optimized 8 NMD‐linked gene prognostic index model were generated by machine learning algorithms in ovarian cancer. Our results provide a new perspective based on NMD status and cell cycle pathways to discriminate subtypes of gBRCA and HRD patients.
Lei Han, Jialing Liu, Runjiao Zhang, Yanan Cheng, Li Dong, Lijuan Wei, Juntian Liu, Ke Wang, Jinpu Yu   +8 more
wiley   +1 more source

Glioma mutational signatures associated with haloalkane exposure are enriched in firefighters. [PDF]

Cancer
Cannataro VL, Bracci PM, Taylor JW, McCoy L, Rice T, Hansen HM, Heffernan AE, Wiemels J, Wiencke J, Wrensch M, Claus EB.   +10 more
europepmc   +1 more source

BRCA1 Promoter Methylation in Ovarian Cancer: Clinical Relevance and a Novel Diagnostic Approach Using Fragment Analysis

Cancer Science, EarlyView.
With the aim of clinical applications, we established a simplified evaluation method for BRCA1 methylation using fragment analysis, called BRCA1‐FAM. We confirmed that high‐grade serous ovarian cancer patients with BRCA1 methylation had poor prognosis.
Saki Tsuchimochi, Yoko Yamamoto, Ayumi Taguchi, Masahito Kawazu, Kenbun Sone, Masako Ikemura, Kana Tamai, Shuhei Kitamura, Daisuke Yoshimoto, Sayuri Fukaya, Aya Ishizaka, Anh Duong Quynh, Akira Nishijima, Yuichiro Miyamoto, Mayuyo Mori, Osamu Hiraike, Kosei Hasegawa, Tetsuo Ushiku, Katsutoshi Oda, Yasushi Hirota, Yutaka Osuga   +20 more
wiley   +1 more source

POLE mutations in endometrial carcinoma: Clinical and genomic landscape from a large prospective single-center cohort. [PDF]

Cancer
Nero C, Trozzi R, Persiani F, Rossi S, Mastrantoni L, Duranti S, Camarda F, Marino I, Giacò L, Pasciuto T, De Bonis M, Rinelli M, Perrone E, Giacomini F, Lorusso D, Piermattei A, Zannoni G, Fanfani F, Scambia G, Minucci A.   +19 more
europepmc   +1 more source

‘Removed With the Stroke of a Pen’: The Hidden Impact of Placement Disruptions on Foster Parents in Norway

Child &Family Social Work, EarlyView.
ABSTRACT This study explores the emotional impact of unplanned removals of foster children on foster parents in Norway. It aims to understand their experiences and identify the support they need during these challenging transitions. We employed a descriptive phenomenological approach. Fouteen in‐depth interviews with 11 foster parents were conducted at
Anette S. Solvi, Marit Råbu, Idun Røseth   +2 more
wiley   +1 more source