Results 301 to 310 of about 21,650,361 (340)

The complexity of tobacco smoke-induced mutagenesis in head and neck cancer. [PDF]

Nat Genet
Torrens L, Moody S, de Carvalho AC, Kazachkova M, Abedi-Ardekani B, Cheema S, Senkin S, Cattiaux T, Cortez Cardoso Penha R, Atkins JR, Gaborieau V, Chopard P, Carreira C, Abbasi A, Bergstrom EN, Vangara R, Wang J, Fitzgerald S, Latimer C, Diaz-Gay M, Jones D, Teague J, Ribeiro Pinto F, Kowalski LP, Polesel J, Giudici F, de Oliveira JC, Lagiou P, Lagiou A, Vilensky M, Mates D, Mates IN, Arantes LM, Reis R, Podesta JRV, von Zeidler SV, Holcatova I, Curado MP, Canova C, Fabianova E, Rodríguez-Urrego PA, Humphreys L, Alexandrov LB, Brennan P, Stratton MR, Perdomo S.   +45 more
europepmc   +1 more source

Digenic Inheritance of Monoallelic MUTYH and POLE Germline Variants in Adrenocortical Carcinoma: Implications for Tumorigenesis and Immunotherapy

Clinical Genetics, EarlyView.
Collision of monoallelic MUTYH and POLE germline variants in a patient with adrenocortical carcinoma who achieved a strong response to immunotherapy.
Jonathan Lopez, Adrien Buisson, Adel Ounnas, Gaelle Tachon, Alain Viari, Florence De Fraipont, Juliette Albuisson, Marc Barritault, Pierre‐Paul Bringuier, Jean‐Paul Feugeas, Anne Mc Leer, Ahmed Bouras   +11 more
wiley   +1 more source

Systematic review of search for meaning in life assessment tools: highlighting the need for a quest for significance scale. [PDF]

Front Psychol
Alsaadi F, Maldonado MA, Erfanikia M, Molinario E, Moyano M.   +4 more
europepmc   +1 more source

Genome‐Wide Screening in Haploid Stem Cells Reveals Synthetic Lethality Targeting MLH1 and TP53 Deficient Tumours

Cell Proliferation, EarlyView.
To identify genetic events that can lead to tumour death once either MLH1 or TP53 is mutated, a genome‐wide genetic screening was performed, uncovering a list of putative hits. Synthetic lethal interactions were validated either genetically or chemically by using small molecules that inhibit these genes either in vitro and in vivo.
Rivki Cashman, Guy Haim‐Abadi, Elyad Lezmi, Hagit Philip, Jonathan Nissenbaum, Ruth Viner‐Breuer, Chen Kozulin, Tamar Golan‐Lev, Aseel Gadban, Shiri Spinner‐Potesky, Ofra Yanuka, Oded Kopper, Nissim Benvenisty   +12 more
wiley   +1 more source

AlphaMissense Predictions and ClinVar Annotations: A Deep Learning Approach to Uveal Melanoma. [PDF]

Ophthalmol Sci
Taylor Gonzalez DJ, Djulbegovic MB, Sharma M, Antonietti M, Kim CK, Uversky VN, Karp CL, Shields CL, Wilson MW.   +8 more
europepmc   +1 more source

Ionospheric model validation using COSMIC 2 - Preliminary results

Pires Morgado Fernandes Pereira, Joana, Borries, Claudia, Fernandez Gomez, Isabel, Heymann, Frank, Schmidt, Michael   +4 more
openaire   +2 more sources

Moral challenges and understanding of clinical ethics in Tanzanian hospitals: Perspectives of healthcare professionals

Developing World Bioethics, EarlyView.
Abstract Healthcare professionals encounter many moral challenges in their daily clinical practice. However, there have been few studies on the subject matter in Tanzania. This study aims to provide an account of moral challenges faced by healthcare professionals in Tanzanian hospitals, their understanding of clinical ethics, and the ethics education ...
Shija Kevin Kuhumba, Bert (A.C) Molewijk, Jan Helge Solbakk, Nandera Ernest Mhando, Trygve Johannes Lereim Sævareid   +4 more
wiley   +1 more source

The Symbolistic Christology in Frantz Fanon's Existentialist Thought

Dialog, EarlyView.
ABSTRACT This article attempts to answer a provocative question: Can existentialist thought provide insights into the nature of Christ? Specifically, what might we learn about Christ from existentialist such as Frantz Fanon, even if only implicitly? In offering a response to the question, I propose a symbolistic Christology through an examination of ...
Chammah J. Kaunda
wiley   +1 more source

Utilization of primary tumor samples for cancer neoantigen discovery. [PDF]

J Immunother Cancer
Leko V, Groh E, Levi ST, Copeland AR, White BS, Gasmi B, Li Y, Hill V, Gurusamy D, Levin N, Kim SP, Sindiri S, Gartner JJ, Prickett TD, Parkhust M, Lowery FJ, Goff SL, Rosenberg SA, Robbins P.   +18 more
europepmc   +1 more source

Manifesto: challenging the standard cosmological model. [PDF]

Philos Trans A Math Phys Eng Sci
Binney J, Mohayaee R, Peacock J, Sarkar S.   +3 more
europepmc   +1 more source