Results 301 to 310 of about 856,925 (387)

Coastal evolution, environmental change and carbon storage in the Thung Prong Thong Mangrove, eastern Gulf of Thailand

Boreas, EarlyView.
Palaeoenvironmental records along the eastern coast of Thailand remain sparse, with only a few studies attempting to reconstruct past climatic and environmental conditions. However, additional palaeoenvironmental, palaeoclimatic and sea‐level records are needed to improve our understanding of coastal evolution and local environmental changes.
Sakonvan Chawchai, Smith Leknettip, Naomi Seaton, Kannika Wangritthikraikul, Nathalie Dubois, Ludvig Löwemark, Pei‐Ling Wang, Frank Preusser   +7 more
wiley   +1 more source

MOV&RSim: computational modelling of cancer-specific variants and sequencing reads characteristics for realistic tumoral sample simulation. [PDF]

BMC Bioinformatics
Longhin F, Baruzzo G, Hazizaj E, Boscarino D, Paladin D, Di Camillo B.   +5 more
europepmc   +1 more source

Refining the timing of Middle Pleistocene (MIS 12 to MIS 6) ice advances into northern central Europe: sedimentological analysis and single‐grain luminescence dating of glaciotectonic complexes and tunnel‐valley fills

Boreas, EarlyView.
We summarize the current state of knowledge on the age of the Middle Pleistocene ice advances into northern central Europe and provide 25 new single‐grain feldspar luminescence ages of Elsterian and Saalian glacigenic sediments to constrain the age of the ice advances and their tentative correlation with marine isotope stages/substages.
Niklas von Soest, Neda Rahimzadeh, Debra Colarossi, Falko Malis, Tobias Lauer, Wera Sander‐Beuermann, Yvonne Spychala, Christian Brandes, Runa Fälber, Sumiko Tsukamoto, Jutta Winsemann   +10 more
wiley   +1 more source

Willingness to participate in a randomized trial of surgical vs. nonoperative care among patients with meniscal tear and knee pain after a course physical therapy. [PDF]

Osteoarthr Cartil Open
Fox KB, Long K, Dhani J, Selzer F, Carland AL, Oh PM, Weiss-Laxer NS, Katz JN.   +7 more
europepmc   +1 more source

PSMD12 Overexpression Promotes Lung Adenocarcinoma Progression via Ubiquitin–Proteasome Pathway Dysregulation

Cancer Science, EarlyView.
PSMD12, located on the frequently amplified 17q region in LUAD, is upregulated in tumors and associated with poor prognosis and advanced stage. Functional studies revealed that PSMD12 promotes cell proliferation and G2/M transition by inhibiting CDK1 ubiquitination and stabilizing CDK1.
Yuya Ono, Hajime Otsu, Takaaki Masuda, Keisuke Kosai, Shohei Shibuta, Kosuke Hirose, Takashi Ofuchi, Yuki Ando, Koto Kawata, Yasuo Tsuda, Yusuke Yonemura, Taro Tobo, Tomoyoshi Takenaka, Tomoharu Yoshizumi, Koshi Mimori   +14 more
wiley   +1 more source

Clinical significance of HPV DNA and EGFR mutations in Egyptian NSCLC. [PDF]

Infect Agent Cancer
Saeed Mohamed S, Hassan ZK, Fahmy AM, Youssef ASE, Fattah NFA, Khater AI, Soliman HK, Hafez MM.   +7 more
europepmc   +1 more source

Precision Oncology for Pediatric Solid Tumors Using In‐Hospital Pediatric/AYA Malignancy‐Specific Panel Sequencing

Cancer Science, EarlyView.
Our findings indicate that a pediatric/AYA‐specific targeted panel deployed in a hospital can deliver rapid, clinically actionable molecular insights with high diagnostic and prognostic yield. This complements larger sequencing platforms by offering speed, focused content, and easier interpretation.
Masato Kojima, Sho Kurihara, Isamu Saeki, Ryo Touge, Keigo Nakashima, Shuhei Karakawa, Fumiyuki Yamasaki, Satoshi Okada, Eiso Hiyama   +8 more
wiley   +1 more source

The genetic landscape of primary malignant melanoma of the cervix using integrated bioinformatics analysis and whole-exome sequencing. [PDF]

Front Oncol
Zhou J, Xu T, Chen C, Ping Y.
europepmc   +1 more source

Refining Tumor Mutational Burden as a Predictive Biomarker for Pembrolizumab: A Real‐World Analysis in Japanese Patients

Cancer Science, EarlyView.
In this study, we investigated the predictive value of tumor mutational burden (TMB) for assessing the efficacy of pembrolizumab in a Japanese cohort. We analyzed real‐world data from 63,952 patients registered in the C‐CAT database who underwent comprehensive genomic profiling, and evaluated the therapeutic efficacy of pembrolizumab in 1899 of these ...
Tomoyo Yasuda, Mio Yumura, Azusa Hamasaki, Tongyi Fei, Takashi Kubo, Hitoshi Ichikawa, Takashi Kohno, Kuniko Sunami   +7 more
wiley   +1 more source