Results 171 to 180 of about 280,610 (238)

Spitz Spindle Cell/Reed Nevus With SQSTM1 :: NTRK2 Fusion and Atypical Features in an Older Male Patient: A Case Report and Review of Literature

Journal of Cutaneous Pathology, Volume 52, Issue 5, Page 367-373, May 2025.
ABSTRACT Spitz lesions display a set of genetic alterations that differ from classical melanocytic lesions: examples include mutations in HRAS and fusions involving ALK, ROS1, MET, MAP3K8, BRAF, and the NTRK genes. We present a Spitz spindle cell/Reed nevus with atypical junctional features and an NTRK2 translocation in a patient of unusual age.
Federico Scarfò, Emanuela Brunetto, Gilda Magliacane, Lorenza Pecciarini, Gerardo Ferrara, Nathalie Rizzo   +5 more
wiley   +1 more source

Genetic profiling of rat gliomas and cardiac schwannomas from life-time radiofrequency radiation exposure study using a targeted next-generation sequencing gene panel.

PLoS ONE
The cancer hazard associated with lifetime exposure to radiofrequency radiation (RFR) was examined in Sprague Dawley (SD) rats at the Ramazzini Institute (RI), Italy. There were increased incidences of gliomas and cardiac schwannomas.
Ashley M Brooks, Andrea Vornoli, Ramesh C Kovi, Thai Vu T Ton, Miaofei Xu, Ahmed Mashal, Eva Tibaldi, Federica Gnudi, Jian-Liang Li, Robert C Sills, John R Bucher, Daniele Mandrioli, Fiorella Belpoggi, Arun R Pandiri   +13 more
doaj   +1 more source

DLSOM: A Deep learning-based strategy for liver cancer subtyping [PDF]

arXiv
Liver cancer is a leading cause of cancer-related mortality worldwide, with its high genetic heterogeneity complicating diagnosis and treatment. This study introduces DLSOM, a deep learning framework utilizing stacked autoencoders to analyze the complete somatic mutation landscape of 1,139 liver cancer samples, covering 20,356 protein-coding genes.
arxiv  

Refined variant calling pipeline on RNA-seq data of breast cancer cell lines without matched-normal samples. [PDF]

BMC Res Notes
Eberth S, Koblitz J, Steenpaß L, Pommerenke C.   +3 more
europepmc   +1 more source

Genomic alterations in normal breast tissues preceding breast cancer diagnosis. [PDF]

Breast Cancer Res
Dai J, Rozenblit M, Li X, Shan NL, Wang Y, Mane S, Marczyk M, Pusztai L.   +7 more
europepmc   +1 more source

Bayesian multi-study non-negative matrix factorization for mutational signatures. [PDF]

Genome Biol
Grabski IN, Trippa L, Parmigiani G.
europepmc   +1 more source

Computational investigation of missense somatic mutations in cancer and potential links to pH-dependence and proteostasis. [PDF]

PLoS One
Sallah S, Warwicker J.
europepmc   +2 more sources

Landscape of TET2 Mutations: From Hematological Malignancies to Solid Tumors. [PDF]

Cancer Med
Hawking ZL, Allan JM.
europepmc   +1 more source

HLA class II-restricted T cell epitopes in public neoantigens of ESR1 and PIK3CA in breast cancer. [PDF]

BMC Cancer
Ando Y, Miyadera H, Bando H, Hashimoto S, Noguchi E, Hara H.   +5 more
europepmc   +1 more source

FAM207A acts as a novel and potential biomarker in lung adenocarcinoma and shapes the immunesuppressive tumor microenvironment. [PDF]

Clin Exp Med
Wang L, Lin F, Yuan J, Wu X, Zhong Y, Li S, Lv Y.   +6 more
europepmc   +1 more source