Results 171 to 180 of about 1,265,099 (265)

The search for the ultimate exercise countermeasure to preserve crew health and ensure mission success in long‐duration spaceflight

Experimental Physiology, Volume 111, Issue 9, Page 3983-3992, 1 September 2026.
Abstract The current understanding of crew health maintenance is founded upon decades of physiological research conducted in terrestrial spaceflight analogues and in low Earth orbit, particularly on the International Space Station. However, as we progress towards the Lunar Gateway and interplanetary missions, it is imperative that the tools employed to
Rodrigo Fernandez‐Gonzalo, Stefan Schneider, Martina Heer, Anna‐Maria Liphardt   +3 more
wiley   +1 more source

Cerebrovascular pulsatility following long duration spaceflight is associated with changes in pulse pressure and carotid artery stiffness

Experimental Physiology, Volume 111, Issue 9, Page 4235-4247, 1 September 2026.
Abstract Central artery stiffening increases the haemodynamic pulsations transmitted downstream towards target organs, including the brain. While recent evidence suggests that long duration spaceflight is associated with reduced common carotid artery (CCA) distensibility, cerebrovascular pulsatility has not been extensively characterized in astronauts.
Roxanne Fournier, Danielle K. Greaves, J. Kevin Shoemaker, Philippe Arbeille, Richard L. Hughson, Andrew D. Robertson   +5 more
wiley   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, Volume 111, Issue 9, Page 4015-4040, 1 September 2026.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Synergistic Effects of UVB and Ionizing Radiation on Human Non-Malignant Cells: Implications for Ozone Depletion and Secondary Cosmic Radiation Exposure. [PDF]

Biomolecules
Gkikoudi A, Manda G, Beinke C, Giesen U, Al-Qaaod A, Dragnea EM, Dobre M, Neagoe IV, Sangsuwan T, Haghdoost S, Vasilopoulos SN, Triantopoulou S, Georgakopoulou A, Tremi I, Koutsoudaki PN, Havaki S, Gorgoulis VG, Kokkoris M, Krasniqi F, Terzoudi GI, Georgakilas AG.   +20 more
europepmc   +1 more source

Sex-specific effects on the heart from combined exposure to simulated galactic cosmic radiation and hindlimb unloading. [PDF]

Life Sci Space Res (Amst)
Nemec-Bakk AS, Sridharan V, Willey JS, Koturbash I, Williams DK, Chesal M, Patel CM, Borg AM, Reno K, Gifford G, Newhauser W, Williams J, Chancellor JC, Boerma M.   +13 more
europepmc   +1 more source

Long-term effects of combined exposures to simulated microgravity and galactic cosmic radiation on the mouse lung: sex-specific epigenetic reprogramming. [PDF]

Radiat Environ Biophys
Clement K, Nemec-Bakk AS, Jun SR, Sridharan V, Patel CM, Williams DK, Newhauser WD, Willey JS, Williams J, Boerma M, Chancellor JC, Koturbash I.   +11 more
europepmc   +1 more source

Tackling aging and chronic disease: How space exploration and the ‘chameleon effect’ of pharmaceuticals can lead the way

Experimental Physiology, Volume 111, Issue 9, Page 4064-4072, 1 September 2026.
Abstract A common misconception surrounding space exploration is that humanity's pursuit of interplanetary travel, such as missions to Mars, is an escape from Earth. In reality, this endeavour offers an invaluable opportunity to address critical biomedical challenges here at home.
Carina Kern, Tina Woods, Keith Siew
wiley   +1 more source

Simulated galactic cosmic radiation-induced cancer progression in mice. [PDF]

Life Sci Space Res (Amst)
Luitel K, Siteni S, Barron S, Shay JW.
europepmc   +1 more source

Cognitive Effects of Simulated Galactic Cosmic Radiation Are Mediated by ApoE Status, Sex, and Environment in APP Knock-In Mice. [PDF]

Int J Mol Sci
Wieg L, Ciola JC, Wasén CC, Gaba F, Colletti BR, Schroeder MK, Hinshaw RG, Ekwudo MN, Holtzman DM, Saito T, Sasaguri H, Saido TC, Cox LM, Lemere CA.   +13 more
europepmc   +1 more source

Simulated Galactic Cosmic Radiation Exposure-Induced Mammary Tumorigenesis in Apc^Min/+ Mice Coincides with Activation of ERα-ERRα-SPP1 Signaling Axis. [PDF]

Cancers (Basel)
Kumar K, Angdisen J, Ma J, Datta K, Fornace AJ, Suman S.   +5 more
europepmc   +1 more source