Results 61 to 70 of about 340,792 (285)

The Cosmos Project: a journey to the stars [PDF]

, 2011
There seems to be some agreement that ‘science for all’ does not necessarily mean ‘one size fits all’ (Lynch, 2001). Teaching scientific disciplines in schools has been traditionally concerned with delivering science as a product with a main focus on its
Kuksa, I, Rumney, P, Scriven, N
core   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Emergent Cosmos in Einstein-Cartan Theory

, 2018
Based on the Padmanabhan's proposal, the accelerated expansion of the universe can be driven by the difference between the surface and bulk degrees of freedom in a region of space, described by the relation $dV/dt=N_{sur}-N_{bulk}$ where $N_{sur}$ and ...
Darabi, F., Hadi, H., Hashemi, M., Heydarzade, Y.   +3 more
core   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source

Cosmos?

, 2023
L’ipotesi dell’eternità della materia/universo è confermata dalle critiche sempre più diffuse e argomentate che va ricevendo il modello (ancora) standard del cosiddetto Big Bang, il quale delineerebbe una problematica singolarità, impossibile da comprendere e persino da studiare sulla base delle leggi conosciute e dei metodi di indagine scientifici.
Mark Williams, Tom Stallard, Jan Zalasiewicz   +2 more
openaire   +3 more sources

Direct Growth of Transparent Boron Nitride Neutron Shielding Layer for Space Window

Advanced Science, EarlyView.
Direct growth of sp2‐sp3 hybridized BN (HBN) on quartz, enabled by an h‐BN buffer, produces transparent and stable films up to 80 µm thick with high transmittance and strong neutron shielding, making HBN a promising candidate for space windows in long‐term lunar missions.
Dobin Kim, Geunpil Kim, Hwijoon Jeong, Sk Mujaffar Hossain, Satadeep Bhattacharjee, Minjae Isaac Kwon, Yeunjeong Lee, Chanhee Yang, Yeong Seok Ham, Taek‐Soo Kim, Hyowon Moon, Inkyu Park, Seung‐Cheol Lee, Jinhwan Kim, Jongbum Kim, Jaehyun Park   +15 more
wiley   +1 more source

Context‐Dependent Role of GDF15: GDF15+ Tumor‐Associated Macrophages Suppress OSCC Progression by Enhancing Phagocytosis

Advanced Science, EarlyView.
This study identifies GDF15+ TAMs as a cell subset mediating tumor regression after immunotherapy. Macrophage‐intrinsic GDF15 enhances phagocytosis and antigen cross‐presentation to CD8+ T cells through the NF‐κB signaling pathway, thereby inhibiting tumor progression.
Xinyu Zhou, Zhihang Zhou, Houyu Ju, Chaoyang Guo, Fangxing Zhu, Yiyi Zhang, Xu Chen, Tongchao Zhao, Laiping Zhong, Jingzhou Hu   +9 more
wiley   +1 more source

Home Army in the Poetry of Jerzy Ficowski

Poznańskie Studia Polonistyczne. Seria Literacka, 2012
The article presents the evolution of the theme of Armia Krajowa (Home Army) and the Warsaw Uprising, in Ficowski’s poetry. The theme, engaged by the poet in the late 1940s (Ołowiani żołnierze, 1948), was quickly abandoned as incompatible with the ...
Jerzy Kandziora
doaj   +1 more source

Passivation‐Induced Species Dynamics and Microstructural Evolution in Solid‐State Lithium–Sulfur Cathodes

Advanced Science, EarlyView.
The formation of insulating Li2S during discharge in solid‐state lithium–sulfur batteries passivate reaction sites and limits sulfur utilization. In this work, a microstructure‐resolved modeling framework coupling transport and reaction kinetics is developed to predict charge–discharge behavior and reveal particle‐scale species evolution and incomplete
Arpan K. Sharma, Bairav S. Vishnugopi, Elif Pınar Alsaç, Matthew T. McDowell, Partha P. Mukherjee   +4 more
wiley   +1 more source

Neutrophil‐Driven Cascade‐Targeted Nanocarriers Restore Mitochondrial Homeostasis to Ameliorate Renal Ischemia–Reperfusion Injury

Advanced Science, EarlyView.
A neutrophil‐mediated dual‐targeting liposome (NKN‐LNP) is developed to treat renal ischemia–reperfusion injury. The system enables spatiotemporally controlled delivery of NMN to injured tubules via MMP‐2/9 activation and KIM1 recognition, restoring mitochondrial function through NAD+‐SIRT3 signaling and preventing the transition from acute kidney ...
Hangbin Ma, Yang Li, Shen Lin, Feifan Chu, Gaozhan Ren, Yinhui Mao, Mingzhi Wu, Yuning Ma, Qiwei Ji, Zujie Chen, Jinzhong Ji, Mingxin Sun, Yongpeng Xu, Xiaoli Sun, Longguang Tang, Hao Zhou   +15 more
wiley   +1 more source