Results 41 to 50 of about 28,214,376 (236)

Cost-effectiveness analysis from sensitivity test.

, 2023
Cost-effectiveness analysis from sensitivity test.
Dickens Odongo (17692177), Bernard Omech (14271358), Alfred Acanga (17692180)   +2 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Cost-effectiveness analysis results across scenarios.

, 2022
Cost-effectiveness analysis results across scenarios.
Timothy O’Brien (3512123), Alexander P. Maxwell (8616429), Paul Cockwell (345149), Matthew D. Griffin (14059596), Luke E. Barry (14059587), Grainne E. Crealey (14059590), Norberto Perico (180737), Ciaran O’Neill (3468947), Stephen J. Elliman (14059593)   +8 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Cost-effectiveness analysis for clinicians

BMC Medicine, 2012
In a climate of economic uncertainty, cost effectiveness analysis is a potentially important tool for making choices about health care interventions. Methods for such analyses are well established, but the results need to be interpreted carefully and are
Hill Suzanne R
doaj   +1 more source

Cost-effectiveness analysis of CBA vs RFA.

, 2022
Cost-effectiveness analysis of CBA vs RFA.
Alireza Darrudi (13007529), Rajabali Daroudi (2824832), Ali Darvishi (9120751), Parham Sadeghipour (12517946)   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A trial-based economic evaluation of the Restore4Stroke self-management intervention compared to an education-based intervention for stroke patients and their partners

BMC Health Services Research, 2020
Background Since stroke survivors are increasingly responsible for managing stroke-related changes in their own health and lifestyle, self-management skills are required.
Ghislaine A. P. G. van Mastrigt, Mitchel van Eeden, Caroline M. van Heugten, Nienke Tielemans, Vera P. M. Schepers, Silvia M. A. A. Evers   +5 more
doaj   +1 more source

Conservation cost‐effectiveness: a review of the evidence base

Conservation Science and Practice, 2021
Prioritizing conservation interventions based on their cost‐effectiveness may enhance global conservation impact. To do this prioritization, conservation decision‐makers need evidence of what works where and how much it costs.
Thomas Pienkowski, Carly Cook, Megha Verma, Luis Roman Carrasco   +3 more
doaj   +1 more source