Results 121 to 130 of about 7,134,173 (343)
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Background Economic evaluation of stroke services indicates that such services may lead to improved quality of life at affordable cost. The present study assesses lifetime health impact and cost consequences of stroke in an integrated service setting ...
Dirks Maaike+5 more
doaj +1 more source
Evaluating cost-effectiveness of diagnostic equipment: the brain scanner case. [PDF]
John R. Bartlett+3 more
openalex +1 more source
The Cost-Effectiveness of Immunohistochemistry
Abstract Objective.—To evaluate the cost-effectiveness of immunohistochemistry. Design.—Using a theoretical decision analytic model, the cost-effectiveness of immunohistochemistry was evaluated in different scenarios depicting the beneficial use of immunohistochemistry.
openaire +3 more sources
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada+3 more
wiley +1 more source
Background Demographic projections suggest a major increase in non-communicable disease (NCD) mortality over the next two decades in developing countries.
Walker Damian+2 more
doaj +1 more source
PROGRAM EVALUATION RESEARCH: AN EXPERIMENTAL COST‐EFFECTIVENESS ANALYSIS OF AN ARMED ROBBERY INTERVENTION PROGRAM [PDF]
John F. Schnelle+5 more
openalex +1 more source
Cost-effectiveness of Colonoscopy [PDF]
This article presents a cost-effectiveness analysis of colorectal cancer screening tests that have been recommended by the United States Preventive Services Task Force, American Cancer Society US Multi-Society Task Force on Colorectal Cancer American College of Radiology, or the American College of Gastroenterology.
openaire +3 more sources
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian+6 more
wiley +1 more source
Earthing effects on mitochondrial function: ATP production and ROS generation
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley +1 more source