Results 71 to 80 of about 4,644,669 (318)

Cost-effectiveness of algorithms [PDF]

Discrete Mathematics & Theoretical Computer Science, 2015
Discrete Algorithms In this paper we discuss how to assess the performance of algorithms for optimisation problems in a way that balances solution quality and time. We propose measures of cost-effectiveness for such algorithms. These measures give the gain in solution quality per time unit over a sequence of inputs, and give a basis for ...
openaire   +4 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Global bibliometric analysis of cost effectiveness analysis in healthcare research from 2013 to 2023

Cost Effectiveness and Resource Allocation
Background Cost-effectiveness analysis (CEA) has become a crucial technique in appraising the efficiency of healthcare interventions and resource allocation decisions.
Kemdi Lugard Okoroiwu, Henshaw Uchechi Okoroiwu, Love Ogochukwu Ude, Chidimma Odilia Ezuma, Emmanuel Ikechukwu Omeje   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Effectiveness and cost-effectiveness of a single home-based fall prevention program: a prospective observational study based on questionnaires and claims data

BMC Geriatrics
Background Fall prevention programmes are essential interventions in societies with aging populations. This study assessed the fall rate and other health outcomes, as well as the cost-effectiveness of a home-based fall prevention programme for community ...
Karin Niedermann, André Meichtry, Barbara Zindel, Markus J. Ernst, Valérie Krafft, Renato Mattli, Irina Nast, Simon Wieser, Markus Wirz, Beatrice Brunner   +9 more
doaj   +1 more source

Hbeag-Negative Chronic Hepatitis B: Cost-Effectiveness of Peginterferon Alfa-2a Compared to Lamivudine in Taiwan

, 2009
Objective: In Taiwan, the carrier rate of hepatitis B surface antigen is 15% to 20%, one of the highest in the world. Among chronic hepatitis B ( CHB) patients, hepatitis B e antigen (HBeAg)-negative accounts for approximately 40% to 50% of these ...
Veenstra, David L.; Sullivan, Sean D.; Lai, Ming-Yang; Lee, Chuan-Mo; Tsai, Chia-Ming; Patel, Kavita K., 賴明陽;李全謨   +1 more
core   +1 more source

Cost-effectiveness of the National Health Service Abdominal Aortic Aneurysm Screening Programme in England. [PDF]

, 2014
BACKGROUND: Implementation of the National Health Service abdominal aortic aneurysm (AAA) screening programme (NAAASP) for men aged 65 years began in England in 2009.
Thompson, SG, Glover, MJ, Kim, LG, Buxton, MJ, Sweeting, MJ   +4 more
core   +1 more source

Cost-Effectiveness Analysis [PDF]

Journal of Nuclear Medicine, 2009
Before any attempt to address the issues implied in the article by Mohan and Miles ( [1][1] ) in this issue of The Journal of Nuclear Medicine , a brief and deliberately simplistic review of methodologic basics may facilitate understanding by nonexpert readers of that article ( [1][1] ). Cost-
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Cost-effectiveness of a proactive, integrated primary care approach for community-dwelling frail older persons

Cost Effectiveness and Resource Allocation, 2019
Background The article reports on the cost-effectiveness of the proactive, integrated primary care program Finding and Follow-up of Frail older persons (FFF) compared with usual primary care for community-dwelling frail older persons in the Netherlands ...
Lotte Vestjens, Jane M. Cramm, Erwin Birnie, Anna P. Nieboer   +3 more
doaj   +1 more source