Results 101 to 110 of about 26,692,564 (286)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

A cost-effectiveness analysis of different therapies in patients with chronic hepatitis B in Italy

ClinicoEconomics and Outcomes Research, 2011
Giorgio L Colombo1,2, Giovanni B Gaeta3, Mauro Viganò4, Sergio Di Matteo21University of Pavia, School of Pharmacy, Italy; 2S.A.V.E. Studi Analisi Valutazioni Economiche, Milan, Italy; 3Viral Hepatitis Unit, Second University, Naples, Italy ...
Giorgio L Colombo, Giovanni B Gaeta, Mauro Viganò, et al   +3 more
doaj  

Cost-effectiveness analysis and its application for policy evaluation for medicine or public health [PDF]

In comparison to the policy for other field, the policy for medicine and public health is to consider the value of life or the value of the quality of life. Quality of life is very well known as a concept of QOL.
Tamie Sugawara, Yasushi Ohkusa
core  

Adaptive pacing, cognitive behaviour therapy, graded exercise, and specialist medical care for chronic fatigue syndrome: a cost-effectiveness analysis. [PDF]

, 2012
BACKGROUND: The PACE trial compared the effectiveness of adding adaptive pacing therapy (APT), cognitive behaviour therapy (CBT), or graded exercise therapy (GET), to specialist medical care (SMC) for patients with chronic fatigue syndrome.
Anthony L. Johnson (124576), McCrone Paul, Trudie Chalder (37639), Johnson Anthony L., Peter D White, Kimberley A Goldsmith, Chalder Trudie, Peter D. White (146167), Goldsmith, Kimberley A., Paul McCrone (121370), McCrone, P, Knapp, M, Martin Knapp (146158), Knapp, Martin, Goldsmith, Kimberley; id_orcid, Chalder, Trudie; id_orcid, Goldsmith, KA, McCrone, Paul R., Sharpe, M, Paul McCrone, Michael Sharpe (146153), Johnson, AL, White Peter D., Goldsmith Kimberley A., Johnson, Anthony L., Sharpe Michael, White, Peter D., Michael Sharpe, Sharpe, Michael, Trudie Chalder, Chalder, Trudie, Knapp Martin, White, PD, Kimberley A. Goldsmith (146164), McCrone, Paul, Anthony L Johnson, Martin Knapp, Chalder, T   +37 more
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Cost-effectiveness analysis of memantine for moderate-to-severe Alzheimer's disease in the Netherlands

Neuropsychiatric Disease and Treatment, 2011
Bart Hoogveldt1, Benoît Rive2, Johan Severens3, Khaled Maman4, Chantal Guilhaume51Field Product Management, Lundbeck BV, Amsterdam, The Netherlands; 2Global Outcomes Research, Lundbeck SAS, Issy-les-Moulineaux, France; 3Institute of Health ...
Hoogveldt B, Rive B, Severens J, Maman K, Guilhaume C   +3 more
doaj  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Economic evaluation of vaccination against COVID‐19: A systematic review

Health Science Reports
Background and Aims Coronavirus has burdened considerable expenditures on the different health systems. Vaccination programs, the critical solution against pandemic diseases, are known as safe and effective interventions to prevent and control epidemics.
Dolatshahi Zeinab, Nargesi Shahin, Mezginejad Fateme, Bagheri Faradonbeh Saeed   +3 more
doaj   +1 more source

Advances in Cost-Effectiveness Analysis of Health Interventions [PDF]

The growing application of cost-effectiveness (CE) analysis and controversies about its methods has led to a need to explore its welfare economic foundations. Examination of its welfare theoretic foundations can provide a rationale for selecting specific
Alan M. Garber
core  

Cost Effectiveness Analysis for Renewable Energy Sources integration in the island of Lemnos, Greece [PDF]

, 2008
The development of more efficient and least cost energy management interventions is of great importance for isolated energy systems. Islands are typical examples of isolated regions, often highly dependent on imported fossil fuels but with a significant ...
Trogadas, P, Assimacopoulos, Dionysis, Assimacopoulos, D, Angelis-Dimakis, A, Trogadas, Panos, Arampatzis, G, Angelis-Dimakis, Athanasios, Arampatzis, George   +7 more
core