Results 91 to 100 of about 713,344 (287)

Noninferiority testing in cost-minimization studies: Practical issues concerning power analysis [PDF]

open access: yes, 2006
Objectives: In cost-minimization studies, it is important to establish noninferiority in the clinical effect of the treatments under investigation. The relationship between the proportion of patients reaching the end point in a study, equivalence limit ...
Stolk, RP   +9 more
core   +1 more source

Cost-effectiveness analysis results.

open access: yes, 2022
Cost-effectiveness analysis results.
Mihaela Nica (3357893)   +5 more
core   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

PHARMACOECONOMIC STUDY OF PRIMARY OPEN-ANGLE GLAUCOMA TREATMENT WITH FIX COMBINATION OF CARBONIC ANHYDRASE INHIBITORS AND BETABLOCKERS

open access: yesФармакоэкономика, 2015
: pharmacoeconomic study of treatment primary open-angle glaucoma with fix combination of carbonic anhydrise inhibitors and betablockers by mean of cost-utility, willingness-to-pay, cost minimization and budget impact analysis was conducted. Results have
M. V. Protsenko
doaj  

Use of pharmacoeconomics in prescribing research. Part 2: cost-minimization analysis -when are two therapies equal?

open access: yes, 2020
This is the second paper in a series looking at pharmacoeconomic methods. The first paper discussed how costs are identified for pharmacoeconomic studies.
BPharm D Newby   +3 more
core  

Cost-benefit analysis of Australian Federal Police counter-terrorism operations at Australian airports [PDF]

open access: yes, 2013
The terrorist attacks of 11 September 2001 highlighted the vulnerabilities of airports and aircraft. Further attacks in 2002, 2007 and 2009, have led to major government reforms in passenger processing and airport access.
John Mueller, Mark G. Stewart
core  

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Cost-Minimization Analysis of Risk-Stratified Hematuria Evaluation

open access: yes, 2016
Background/Aims: Up to 30% of adults have hematuria; however, 5% or fewer have a significant finding such as bladder or kidney cancer. Current guidelines recommend cystoscopy and imaging for all who meet criteria; however, the guidelines acknowledge ...
Kirchner, H. Lester   +7 more
core   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Cost Minimization Analysis of Oral Antidiabetic Drugs in Type II Diabetes Mellitus Patiens at Sultan Suriansyah Hospital January-December 2022 Period

open access: yesBerkala Kedokteran
Diabetes According to WHO (2016) is a serious chronic disease that occurs when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces.
Farah Noor Ain   +2 more
doaj   +1 more source

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