Results 61 to 70 of about 4,271,269 (288)

Cost-utility analysis of newborn hepatitis B immunization in Beijing

Human Vaccines & Immunotherapeutics, 2021
Objectives To evaluate cost-utility of universal Hepatitis B vaccination program in the Beijing city (Beijing). Methods A decision-Markov model was constructed to determine the cost-utility of the universal immunization program for infants (universal ...
Yiwei Guo, Yong Yang, Qian Bai, Zhengwei Huang, Zongwu Wang, Dongxia Cai, Shuo Li, Xiaowei Man, Xuefeng Shi   +8 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Measuring the health benefits of genome and exome sequencing: a systematic review of economic evaluations

Frontiers in Public Health
IntroductionGenome sequencing (GS) and exome sequencing (ES) technologies have gained increasing attention in health economics for evaluating their clinical and public health introduction, but their complexity challenges traditional methods.
Marianna Riccio, Annalisa Rosso, Leonardo Maria Siena, Valentina Baccolini, Valentina Baccolini, Giuseppe Migliara, Antonio Sciurti, Claudia Isonne, Jessica Iera, Francesco Pierri, Carolina Marzuillo, Corrado De Vito, Giuseppe La Torre, Paolo Villari   +13 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Other title: House Resolution 5005 - Testimony on Behalf of the Citizens' Utility Ratepayer Board by David Springe, Consumer Counsel

, 2011
application/pdf; "January 27, 2011."; Testimony before the Kansas Legislature, House Utilities Committee, presented by David Springe, Consumer Counsel, Citizens' Utility Ratepayer Board.Testimony in opposition to House Resolution 5005.
Springe, David.
core   +1 more source

Cost-effectiveness of a victim improvement package: randomised controlled trial for reduction of continued symptoms of depression or anxiety in older victims of community crime

BJPsych Open
Background Crime has significant impact on older victims. High rates of anxiety and depression may be associated with crimes. Aims This paper aims to evaluate the cost-effectiveness of a victim improvement package (VIP) for the reduction of continued
Monica Panca, Marc Serfaty, Jessica Satchell, Rachael Maree Hunter   +3 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Other title: House Bill 2711 - Testimony on Behalf of the Citizens' Utility Ratepayer Board by David Springe, Consumer Counsel

, 2008
application/pdf; "February 6, 2008."; Includes a copy of testimony on House Bill 2682 presented before the Kansas Legislature, House Utilities Committee, by David Springe, Consumer Counsel, Citizens' Utility Ratepayer Board on January 31, 2008.;
Springe, David.
core   +1 more source

Cost-effectiveness and budget impact of the fixed-dose dual bronchodilator combination tiotropium–olodaterol for patients with COPD in the Netherlands

International Journal of COPD, 2016
Job FM van Boven,1,2 Janwillem WH Kocks,2 Maarten J Postma1,3,4 1Department of Pharmacy, Unit of PharmacoEpidemiology & PharmacoEconomics, 2Department of General Practice, Groningen Research Institute for Asthma and COPD (GRIAC), 3Institute of ...
van Boven JF, Kocks JWH, Postma MJ
doaj  

Cost-effectiveness of MLC601 in post-stroke functional recovery compared with placebo - the CHIMES & CHIMES-E studies

BMC Health Services Research
Background Despite progress in stroke therapy (e.g., revascularisation interventions by thrombolysis and/or thrombectomy, organised stroke care), many stroke survivors will have impairment of neurological function.
Christopher Li Hsian Chen, Jia Hui Chai, Yogesh Mahadev Pokharkar, Narayanaswamy Venketasubramanian   +3 more
doaj   +1 more source