Results 91 to 100 of about 1,913,764 (268)

Exploitation of Mineral Resources in Conditions of Volatile Energy Prices: Technical and Economic Analysis of Low-Quality Deposits

Energies
In mining projects and production operations, energy carrier costs (fuel, electricity) constitute the primary component of variable costs. This study outlines a methodology for projecting operating costs in a surface mine or quarry in order to find the ...
Zbigniew Krysa, Przemysław Bodziony, Michał Patyk   +2 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Promoting The Integrated Community Case Management of Under-Five Pneumonia In Nigeria: A Cost-Benefit Analysis [PDF]

, 2020
Charles Okafor, Obinna Ikechukwu Ekwunife   +1 more
openalex   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Cost-effectiveness analysis of using the TBX6-associated congenital scoliosis risk score (TACScore) in genetic diagnosis of congenital scoliosis

, 2020
Zefu Chen, Zihui Yan, Chenxi Yu, Jiaqi Liu, Yanbin Zhang, Sen Zhao, Jiachen Lin, Yuanqiang Zhang, Lianlei Wang, Mao Lin, Sen Zhao, Xiaoxin Li, Yuchen Niu, Shengru Wang, Zhihong Wu, Guixing Qiu, Zhihong Wu, Jianguo Zhang, Nan Wu, Lan Zhu, Shengru Wang, Na Chen, Jiaqi Liu, Sen Liu, Yuzhi Zuo, Gang Liu, Yuanqiang Zhang, Chenxi Yu, Sen Zhao, Lianlei Wang, Yanxue Zhao, Wei‐Sheng Chen, Zihui Yan, Xinzhuang Yang, Hengqiang Zhao, Yuchen Niu, Jingdan Chen, Xiaoxin Li, Huizi Wang, Zhi Gang Zhao, yiran cui, Zixin Zhang, Zefu Chen, Bowen Liu, Xi Cheng, Mao Lin, Jiachen Lin, Huakang Du, Yaqi Li, Yi You, Guixing Qiu, Jianguo Zhang, Nan Wu, Nan Wu   +53 more
openalex   +1 more source

A Simulation Study on Energy Consumption and Cost Analysis of Hybrid Electric Motorcycle [PDF]

, 2018
Nguyen Van Cuong, Pham Tuan Anh, Thinh Huynh   +2 more
openalex   +1 more source

Impact and cost‐effectiveness of the national scale‐up of HIV pre‐exposure prophylaxis among female sex workers in South Africa: a modelling analysis [PDF]

, 2023
Jack Stone, Rutendo Bothma, Gabriela B. Gomez, Robyn Eakle, Christinah Mukandavire, Hasina Subedar, Hannah Fraser, Marie‐Claude Boily, Sheree Schwartz, Jenny Coetzee, Kennedy Otwombe, Minja Milovanovic, Stefan Baral, Leigh F. Johnson, François Venter, Helen Rees, Peter Vickerman   +16 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source