Results 91 to 100 of about 7,336,661 (310)

OPTIC—OPtimized Translation and Interaction for Cloud-Costs: Use of FOCUS Standardization and LLM Integration for Cloud Billing Analysis

IEEE Access
Managing billing data across multicloud environments remains a significant challenge due to heterogeneous data formats, fragmented cost metrics, and the technical complexity of cost analysis.
Gilberto N. Junior, Cesar Marcon
doaj   +1 more source

Cost Analysis in Patients Treated with Partial Laryngectomy

Turkish Archives of Otorhinolaryngology, 2013
Objective:The aim of this study was to conduct a cost analysis in patients treated with partial laryngectomy surgery due to laryngeal carcinoma.Methods:The length of stay, complication rates, decannulation time, time to initiate oral nutrition, costs of ...
Esra Sözen, Yusuf Orhan Uçal, Gülpembe Talayhan, Hasan Deniz Tansuker, Berna Uslu Coşkun   +4 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Cost-Benefit Analysis and the Marginal Cost of Public Funds [PDF]

The marginal cost of public funds defined as the ratio between the shadow price of tax revenues and the population average of the social marginal utility of income, is analysed within an explicit cost–benefit context.
Lundholm, Michael
core  

Sensitivity analysis of key operating parameters of combine harvesters

Research in Agricultural Engineering, 2016
The sensitivity analysis of key operating parameters on the average annual sub-profit in a group of three combine harvesters operating in companies providing agricultural services were analysed.
M. Kavka, M. Mimra, F. Kumhála
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Reliability and cost: A sensitivity analysis [PDF]

In the design phase of a system, how a design engineer or manager choose between a subsystem with .990 reliability and a more costly subsystem with .995 reliability is examined, along with the justification of the increased cost.
Patterson, Richard L., Suich, Ronald C.
core   +1 more source

Health-related Quality of Life and hospital costs of Finnish melanoma patients participating in the second Multicenter Selective Lymphadenectomy Trial (MSLT-II)

Acta Oncologica
Background and purpose: After reports that complete lymph node dissection (CLND) did not improve melanoma-specific survival of sentinel lymph node (SLN)-positive patients, the use of CLND has diminished but it is still carried out for selected patients ...
Pia J. Heino, Jukka Pappinen, John F. Thompson, Micaela Hernberg, Tiina A. Jahkola, Mark B. Faries   +5 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Safety, efficacy and total cost of point-of-care manufactured anti-CD19 CAR-T cell therapy in India: VELCART trial

Molecular Therapy: Oncology
Decentralized or point-of-care (POC) manufacture of CAR-T cells is a potential strategy to improve accessibility and reduce cost and logistic challenges.
Hamenth Kumar Palani, Arun Kumar Arunachalam, Uday Kulkarni, Mohammed Yasar, Arvind Venkatraman, Swathy Palanikumar, Reeshma Nair Radhakrishnan, Majeela Solomon, Abirami Rajasekaran, Aniket Bankar, Phaneendra Venkateswara Rao Datari, Sushil Selvarajan, Anu Korula, Pradyot Dash, Dina Schneider, Louisa Wirthlin, Aby Abraham, Biju George, Vikram Mathews   +18 more
doaj   +1 more source