Results 91 to 100 of about 879,626 (269)

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

Impact of national volume-based procurement reform on the markup of pharmaceutical firms: an event study

open access: yesCost Effectiveness and Resource Allocation
Background In 2018, China’s National Healthcare Security Administration initiated a transformation of drug procurement towards national volume-based procurement (NVBP) of drugs, which disclosed the quantity information in the procurement auction ...
Ran Yan, Zhuang Miao, Fuguo Cao
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

Restricting tobacco sales to only pharmacies as an endgame strategy: are pharmacies likely to opt in?

open access: yesAustralian and New Zealand Journal of Public Health, 2018
Frederieke Sanne Petrović‐van der Deen   +1 more
doaj   +1 more source

A cost-utility analysis of Glecaprevir/Pibrentasvir versus Sofosbuvir/Daclatasvir and Sofosbuvir/Velpatasvir for treatment of hepatitis C in Iran

open access: yesCost Effectiveness and Resource Allocation
Objectives New antiviral medications for hepatitis C can significantly reduce liver disease risk, and decrease mortality rates and associated costs.
Mojtaba Jafari   +6 more
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

Associations of Alzheimer’s disease with inpatient hospital costs and with quality-adjusted life years: evidence from conventional and Mendelian randomization analyses in the UK Biobank

open access: yesCost Effectiveness and Resource Allocation
Background Alzheimer’s disease is a progressive neurodegenerative disorders with profound impacts on cognitive function. There is a shortage of economic evidence relating to the impact that Alzheimer’s disease has on healthcare costs and quality-adjusted
Padraig Dixon, Emma Anderson
doaj   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

open access: yesFEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li   +7 more
wiley   +1 more source

Health economics in Africa: historical perspectives, current challenges, and policy recommendations for sustainable healthcare financing and resource allocation

open access: yesCost Effectiveness and Resource Allocation
Health economics is crucial for optimizing resource allocation and achieving equitable health outcomes in Africa. This study reviewed the historical evolution and current state of health economics in Africa, focusing on healthcare financing mechanisms ...
Oche Joseph Otorkpa   +2 more
doaj   +1 more source

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