Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
A Modelling Approach for Evaluating Agri-Environmental Policies at Sector Level [PDF]
This paper presents a new approach to evaluate the cost effectiveness of agri-environmental policies at sector level. Policy uptake, cumulative environmental effects and public expenditure are identified as the main determinants of cost-effectiveness. On
Lampkin, N. H. +4 more
core
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Differential discounting in the economic evaluation of healthcare programs
Background The question of appropriate discount rates in health economic evaluations has been a point of continuous scientific debate. Today, it is widely accepted that, under certain conditions regarding the social objective of the healthcare decision ...
Jürgen John +2 more
doaj +1 more source
The cost-effectiveness of drug-eluting stents: a systematic review [PDF]
Suzanne A. Ligthart +3 more
openalex +1 more source
EE8 Cost-Effectiveness and Cost-Utility of a Digital Wellness Intervention for Managing Depression and Anxiety: An Employer Perspective [PDF]
A Mohandas +3 more
openalex +1 more source
Cost-effectiveness of voluntary HIV-1 counseling and testing in reducing sexual transmission of HIV-1 in Kenya and Tanzania. [PDF]
Background Access to HIV-1 voluntary counseling and testing (VCT) is severely limited in less-developed countries. We undertook a multisite trial of HIV-1 VCT to assess its impact, cost, and cost-effectiveness in less-developed country settings.\ud ...
Balmer, D +7 more
core
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
EE34 Comparing the Cost-Effectiveness of the Otago Exercise Programme Among Older Women and Men: A Secondary Analysis of a Randomized Controlled Trial [PDF]
Joshua L. Davis +11 more
openalex +1 more source
Cost effectiveness of spacecraft pointing antennas [PDF]
Comparative cost analysis of spacecraft pointing antennas and RF tracking ...
Dickinson, R. M.
core +1 more source

