Results 61 to 70 of about 419,459 (295)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Cost-effectiveness of CPAP treatment in a tax-funded healthcare system – a scoping review and suggestions for cost reduction of CPAP treatment

open access: yesEuropean Clinical Respiratory Journal
Aims Obstructive sleep apnoea (OSA) is an increasing global public health problem. The primary treatment option is continuous positive airway pressure (CPAP).
Tiina Mattila   +5 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Operational asset replacement strategy : a real options approach [PDF]

open access: yes, 2009
This article analyses the problem of replacement by investigating the optimal moment of investment replacement in a given tax environment with a given depreciation policy.
Duque, João, Zambujal, João
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Minimizing Costs Can Be Costly [PDF]

open access: yesAdvances in Decision Sciences, 2010
A quite common practice, even in academic literature, is to simplify a decision problem and model it as a cost-minimizing problem. In fact, some type of models has been standardized to minimization problems, like Quadratic Assignment Problems (QAPs), where a maximization formulation would be treated as a “generalized” QAP and not solvable by many of ...
openaire   +2 more sources

Efficiency in Deregulated Electricity Markets: Offer Cost Minimization vs. Payment Cost Minimization Auction

open access: yes, 2007
A payment cost minimization (PCM) auction has been proposed to solve the problem of inflated wholesale electricity prices. In the electricity industry, where even small changes in $/MW are worth tens of millions of dollars, it is highly important that ...
Baltaduonis, Rimvydas
core  

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

Efficient Minimization of Routing Cost in Wireless Networks

open access: yesJournal of Engineering and Sustainable Development, 2013
This paper studies how to select a path with the minimum cost .the networks are characterized by limited computational and power source capabilities. Thus, it is necessary to provide an efficient method for producing routing decisions. Wireless networks
Anas Ali Hussien, Sarah Yahia Ali
doaj  

Minimizing Geo-Distributed Interactive Service Cost With Multiple Cloud Service Providers

open access: yesIEEE Access, 2019
Geo-distributed interactive service is a type of Internet cloud service. Since data centers belonging to multiple cloud service providers (CSPs) can provide lower resource provision cost for these services, we try to overcome the two challenges in ...
Fei Hu   +3 more
doaj   +1 more source

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