Results 61 to 70 of about 54,352 (246)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Cost minimization analysis of using «Ethanol wipes «МК Aseptic»»

Качественная клиническая практика, 2018
It was conducted cost-minimization analysis (CMA) for use in a hospital medical product «Ethanol wipes «МК Aseptic»» in comparison with «routine» practice of making and using gauze (or cotton balls) and 70% ethanol or 70% isopropyl alcohol. CMA has shown
D. Yu. Belousov, E. V. Afanasyeva
doaj  

Comparative efficacy and safety between amisulpride and olanzapine in schizophrenia treatment and a cost analysis in China: a systematic review, meta-analysis, and cost-minimization analysis

BMC Psychiatry, 2018
Background Amisulpride was introduced into China in 2010 as a second-generation atypical antipsychotic, while olanzapine has been on the market since 1999 as one of the leading treatments for schizophrenia in China.
Peng Men, Zhanmiao Yi, Chaoyun Li, Shuli Qu, Tengbin Xiong, Xin Yu, Suodi Zhai   +6 more
doaj   +1 more source

Minimization of carbon abatement cost: Modeling, analysis and simulation

Discrete and Continuous Dynamical Systems - B, 2017
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Yang, Xiaoli, Liang, Jin, Hu, Bei
openaire   +3 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Cost-effectiveness analysis in minimally invasive spine surgery

Neurosurgical Focus, 2014
Object Medical care has been evolving with the increased influence of a value-based health care system. As a result, more emphasis is being placed on ensuring cost-effectiveness and utility in the services provided to patients.
Lutfi T, Al-Khouja, Eli M, Baron, J Patrick, Johnson, Terrence T, Kim, Doniel, Drazin   +4 more
openaire   +2 more sources

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Cost analysis of vitrectomy under local versus general anesthesia in a developing country

Clinical Ophthalmology, 2018
Gilbert WS Simanjuntak,1–3 Ari Djatikusumo,4 Asri Adisasmita,5 Mardiati Nadjib,6 HHB Mailangkay,1 Nazimul Hussain7 1Department of Ophthalmology, Faculty of Medicine, Christian University of Indonesia, Jakarta, Indonesia; 2Cikini Eye Institute ...
Simanjuntak GWS, Djatikusumo A, Adisasmita A, Nadjib M, Mailangkay HHB, Hussain N   +5 more
doaj  

COST-MINIMIZATION OF VILANTEROL / UMECLIDINIUM VERSUS OLODATEROL / TIOTROPIUM IN THE BASIC THERAPY OF SEVERE AND VERY SEVERE COPD

Фармакоэкономика, 2017
The recently introduced novel drug combinations for the treatment of COPD are based on long-acting beta-agonists (vilantererol / umeclidinum bromide) and long-acting anticholinergics (olodaterol / tiotropium bromide).
E. G. Kosolapov, F. S. Kochenkov, N. L. Pogudina, D. V. Blinov, N. L. Bondarenko, A. V. Karaulov   +5 more
doaj   +1 more source