Results 91 to 100 of about 297,525 (311)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

open access: yesAdvanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales   +11 more
wiley   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

open access: yesAdvanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement   +12 more
wiley   +1 more source

Annual societal cost of Alzheimer’s disease in Malaysia: a micro-costing approach

open access: yesBMC Geriatrics
Background Alzheimer’s disease (AD) is expected to have a significant impact on resource use and economic consequences along with population aging. This study aims to investigate the annual economic burden of Alzheimer’s disease along with underlying ...
Siew Chin Ong   +5 more
doaj   +1 more source

A consensus-based checklist for the critical appraisal of cost-of-illness (COI) studies [PDF]

open access: hybrid, 2023
Lena Schnitzler   +4 more
openalex   +1 more source

Highly Tunable and Cell‐Remodelable Thiol‐ene Alginate‐Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication

open access: yesAdvanced Healthcare Materials, EarlyView.
Norbornene‐functionalized alginate is crosslinked with a di‐thiolated peptide sequence cleavable by cell‐secreted matrix metalloproteinases and decorated with cell‐adhesion peptides upon exposure to UV. Thyroid follicles, endometrial and intestinal organoids are encapsulated in a gentle manner with high cell viability and correct phenotype ...
Julia Fernández‐Pérez   +8 more
wiley   +1 more source

The incremental healthcare cost associated with cancer in Belgium: A registry‐based data analysis

open access: yesCancer Medicine
Background Similar to many countries, Belgium experienced a rapid increase in cancer diagnoses in the last years. Considering that a large part of cancer types could be prevented, our study aimed to estimate the annual healthcare burden of cancer per ...
Vanessa Gorasso   +10 more
doaj   +1 more source

Economic burden of COVID-19, China, January–March, 2020: a cost-of-illness study

open access: diamond, 2020
Huajie Jin   +7 more
openalex   +1 more source

3D‐Printed Gastrointestinal Stents: In Vivo Evaluation in a Swine Small Bowel Perforation Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Gastrointestinal fistulae and perforations can lead to severe complications including sepsis and patient death. In this work, the efficacy of 3D‐printed gastrointestinal stents composed of poly‐lactic‐acid (PLA) was evaluated in an in vivo swine model.
Gweniviere Capron   +9 more
wiley   +1 more source

Cost of illness in patients with metastatic colorectal cancer [PDF]

open access: bronze, 2010
Xue Song   +5 more
openalex   +1 more source

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