Results 91 to 100 of about 1,642,794 (296)
Separable Concave Optimization Approximately Equals Piecewise-Linear Optimization [PDF]
, 2012 We study the problem of minimizing a nonnegative separable concave function over a compact feasible set. We approximate this problem to within a factor of 1+epsilon by a piecewise-linear minimization problem over the same feasible set. Our main result is
Magnanti, Thomas L., Stratila, Dan
core +1 more source
Locality-Aware Hybrid Coded MapReduce for Server-Rack Architecture
, 2017 MapReduce is a widely used framework for distributed computing. Data shuffling between the Map phase and Reduce phase of a job involves a large amount of data transfer across servers, which in turn accounts for increase in job completion time.
Gupta, Sneh, Lalitha, V.
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Profit Maximization for Online Advertising Demand-Side Platforms
, 2017 We develop an optimization model and corresponding algorithm for the management of a demand-side platform (DSP), whereby the DSP aims to maximize its own profit while acquiring valuable impressions for its advertiser clients.
Grigas, Paul +3 more
core +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Machine Learning and Knowledge ExtractionIn edge-assisted low-latency video analytics, a critical challenge is balancing on-device inference latency against the high bandwidth costs and network delays of offloading. Ineffectively managing this trade-off degrades performance and hinders critical
Yan Lyu +5 more
doaj +1 more source
Optimization of Replaced Grinding Wheel Diameter for Surface Grinding Based on a Cost Analysis
Metals, 2019 Based on a cost analysis, a method of identifying and predicting optimum replaced grinding wheel diameter (De.op) in a surface grinding operation for 9CrSi steel material was developed in this study.
Thi-Hong Tran +8 more
doaj +1 more source
Variational method in the design of an optimum solar water heater storage tank [PDF]
, 2007 Solar water heaters are now have been accepted as a reliable source of providing hot water heating in many domestic homes and are becoming more popular. Unfortunately, solar water heaters are still considered luxurious hardware in Malaysia. A cheaper and
Darus, Amer Nordin, Misha, Suhaimi
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source