Results 61 to 70 of about 1,642,794 (296)
Random Costs in Combinatorial Optimization [PDF]
Physical Review Letters, 2000 The random cost problem is the problem of finding the minimum in an exponentially long list of random numbers. By definition, this problem cannot be solved faster than by exhaustive search. It is shown that a classical NP-hard optimization problem, number partitioning, is essentially equivalent to the random cost problem.
openaire +3 more sources
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Cost optimization on example of hotel-restaurant complex enterprises
Проблеми теорії та методології бухгалтерського обліку, контролю і аналізу, 2017 Optimization of costs is important for increasing competitiveness and profitability of the enterprise, therefore, the purpose of the study is to establish and visualize the basis of cost optimization on the example of hotel-restaurant complex enterprises.
Volkovska I.V.
doaj +1 more source
Optimization of return value and handling cost [PDF]
, 1992 This paper discusses the application of Operations Research methodology in aiding manager in decision making regarding assignment and transportation problem.
Maarof, Faridah
core
Topological optimization via cost penalization
, 2019 We consider general shape optimization problems governed by Dirichlet boundary value problems. The proposed approach may be extended to other boundary conditions as well. It is based on a recent representation result for implicitly defined manifolds, due
Murea, Cornel Marius, Tiba, Dan
core +1 more source
A multifidelity multiobjective optimization framework for high-lift airfoils [PDF]
, 2016 High-lift devices design is a challenging task as it involves highly complex flow features while being critical for the overall performance of the aircraft.
Demange, Jean +2 more
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Учёт. Анализ. Аудит, 2019 Overhead costs are an obstacle between the customers and the executors of the state defense order. The problem of their reduction was repeatedly highlighted and considered, but, in the absence of a simple decision regarding this issue, it was never ...
Anna Aleksandrovna Bakulina +2 more
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source