Results 71 to 80 of about 1,642,794 (296)

Hydraulic Modelling and Optimization of a Wastewater Treatment System for Developing Nations Using Computational Fluid Dynamics [PDF]

, 2012
Waste stabilization pond (WSP) is globally one of the most popular wastewater treatment options because of its high efficiency and low cost. However, no rigorous assessment of WSPs that account for cost in addition to hydrodynamics and treatment ...
Adekalu, K.O., Ducoste, J.J., Olukanni, D. O.   +2 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Cost-Optimal Aggregated Electric Vehicle Flexibility for Demand Response Market Participation by Workplace Electric Vehicle Charging Aggregators

Energies
In recent years, with the growing number of EV charging stations integrated into the grid, optimizing the aggregated EV load based on individual EV flexibility has drawn aggregators’ attention as a way to regulate the grid and provide grid services, such
Yi-An Chen, Wente Zeng, Adil Khurram, Jan Kleissl   +3 more
doaj   +1 more source

Optimization of structures on the basis of fracture mechanics and reliability criteria [PDF]

, 1973
Systematic summary of factors which are involved in optimization of given structural configuration is part of report resulting from study of analysis of objective function.
Heer, E., Yang, J. N.
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Optimization of Electricity Consumption-Associated Costs in a Medium-Sized Logistics Company

Energies
The purpose of this research is to investigate the possibilities of electricity consumption-associated cost reduction in buildings owned by a medium-sized logistics company in Latvia (A_LV), which is a part of the larger international business ecosystem (
Martins Tisenkopfs, Leo Jansons, Ineta Geipele, Sanda Lapuke, Andris Backurs   +4 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Mitigating the Cost Amplification of Platform Defaults in Lean Cloud Data Deployments Through Configuration Hygiene

Transactions on Informatics and Data Science
Cloud data platforms offer flexibility, but their default configurations are implicitly optimized for enterprise-scale environments, leading to hidden, disproportionate costs for small-scale deployments. This paper introduces the concept of a silent tax,
Manuel O. Diaz
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Cost Optimization of Wastewater and Septage Treatment Process

Energies, 2020
Analysis of the current knowledge has revealed the lack of a method for increasing the cost-effectiveness of wastewater and septage treatment in plants overloaded by contamination.
Beata Karolinczak, Rafał Miłaszewski, Wojciech Dąbrowski   +2 more
doaj   +1 more source