Results 31 to 40 of about 233,709 (257)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Farmers' Preferences for Crop Contracts

open access: yesJournal of Agricultural and Resource Economics, 1997
An empirical approach combining elements of principal-agent theory and transaction cost economics is used to determine farmers' preferences for contract terms in crop production. The approach is tested by asking grain farmers to rank contract choices and
Kaouthar Lajili   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Quantifying the uptake of climate services at micro and macro level

open access: yesClimate Services, 2020
Quantification and communication of the expected net benefits of climate services for particular types of users and society at large has been hitherto a rather weak element in the deployment of climate services.
Adriaan Perrels
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Dynamic Matching in Cloud Manufacturing considering Matching Costs

open access: yesComplexity, 2019
As a service-oriented business platform model, the nature of cloud manufacturing is to realise the manufacturing resources’ sharing, which will largely benefit resources supplier, resources demander, and platform operator. However, it also faces some new
Qi Chen, Qi Xu, Cui Wu
doaj   +1 more source

Application of Cost Allocation Concepts of Game Theory Approach for Cost Sharing Process

open access: yesResearch Journal of Applied Sciences, Engineering and Technology, 2013
Dissatisfaction among involved parties regarding the ways of cost allocation is ordinary in the joint ventures, since each party attempts to get more interest caused by making the coalition. Various cost allocation methods such as proportional methods, some methods in cooperative game theory approach and etc have been used for the purpose of cost ...
Mojtaba Valinejad Shoubi   +2 more
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Supply Chain Inventory Sharing Using Ethereum Blockchain and Smart Contracts

open access: yesIEEE Access, 2022
Information sharing is essential for coordination and stakeholder integration and is crucial to achieving sustainable supply chain operations. Furthermore, improved information sharing assists retailers by reducing the time spent looking for alternative ...
Ilhaam A. Omar   +5 more
doaj   +1 more source

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