Results 41 to 50 of about 4,416,612 (247)

Pharmaceutical portfolio optimization under cost uncertainty via chance constrained-type method

Journal of Mathematics in Industry, 2021
Project selection for a portfolio is a pivotal decision in the pharmaceutical industry. In this paper, we study a portfolio optimization problem for pharmaceutical companies considering the uncertainty of the cost of each phase of drug development and ...
Maboubeh Farid, Abraar Chaudhry, Magnus Ytterstad, Stig Johan Wiklund   +3 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

The COST 731 Action : a review on uncertainty propagation in advanced hydro-meteorological forecast systems [PDF]

, 2010
Quantifying uncertainty in flood forecasting is a difficult task, given the multiple and strongly nonlinear model components involved in such a system.
Massimiliano Zappa, Liechti, Katharina, Peter Krahe, Krahe, P. (Peter), Rossa, Andrea, Christian Keil, Katharina Liechti, Urs Germann, Michael Bruen, Zappa, Massimiliano, Haase, Günther, Andrea Rossa, Bruen, Michael, Germann, Urs, Keil, Christian, Günther Haase   +15 more
core   +1 more source

Fair Cost Allocation in Energy Communities Under Forecast Uncertainty

IEEE Open Access Journal of Power and Energy
Energy communities (ECs) are an increasingly studied path toward improving prosumer coordination. A central challenge of ECs is to allocate cost savings fairly to members. While many allocation mechanisms have been developed, existing literature does not
Michael Eichelbeck, Matthias Althoff
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Algorithms for Optimal Power Flow Extended to Controllable Renewable Systems and Loads

Algorithms, 2021
In an effort to quantify and manage uncertainties inside power systems with penetration of renewable energy, uncertainty costs have been defined and different uncertainty cost functions have been calculated for different types of generators and electric ...
Elkin D. Reyes, Sergio Rivera
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Cost engineering for manufacturing: current and future research [PDF]

, 2011
This paper aims to review the current practice in cost engineering, identify the scientific research challenges and suggest future direction of this area research.
E. Shehab (7211669), Cheung, Wai Ming, Erkoyuncu, J. A., Newnes, Linda, Roy, R.,, Wang, Qing, Shehab, E., Baguley, P.,, P. Arundachawat (7211666), P. Baguley, J.A. Erkoyuncu (7211654), F. Elgh (7211651), Shehab, E.,, Wang, Q., Erkoyuncu, John Ahmed, Q. Wang, Cheung, W. M., Xu, Y., Q. Wang (782488), Roy, R., Yee Goh (1256379), Baguley, P., Goh, Yee Mey, Arundachawat, P.,, F. Elgh, Goh, Y.,, Elgh, Fredrik,, Bankole, O.,, R. Roy, Newnes, L.,, Baguley, Paul, Y. Goh, Shehab, Essam, Cheung, W. M.,, E. Shehab, O. Bankole (7211657), Newnes, L., Cheung, W.M., Y. Xu (741407), Erkoyuncu, J.A., Y. Xu, Roy, Rajkumar, O. Bankole, Wang, Q.,, J. A. Erkoyuncu, Goh, Y., R. Roy (2538628), Elgh, F., Arundachawat, Panumas, Bankole, O., Xu, Yuchun,, Linda B. Newnes (7204940), W. M. Cheung, P. Baguley (7211663), Erkoyuncu, John,, Xu, Yuchun, Bankole, Oyetola, L. Newnes, P. Arundachawat, Arundachawat, P., W.M. Cheung (7211660)   +60 more
core   +1 more source

Firm-level climate policy uncertainty perception and the cost of equity capital: evidence from textual analysis

Journal of Applied Economics
We construct a new firm-level climate policy uncertainty perception using textual data from the annual reports of Chinese listed firms, and investigate the effect of climate policy uncertainty perception on the cost of equity capital.
Di Hu, Shuxin Zhang, Tong Fang
doaj   +1 more source

A critical assessment framework to identify, quantify and interpret the sources of uncertainty in cost-effectiveness analyses

BMC Health Services Research, 2022
Background Using a standardized approach to describe the sources of uncertainty in cost-effectiveness analyses might bring added value to the local critical assessment procedure of reimbursement submissions in Hungary.
Gergő Merész, Veronika Dóczy, Áron Hölgyesi, Gergely Németh   +3 more
doaj   +1 more source