Results 101 to 110 of about 3,740,458 (303)
Advanced Science, EarlyView.Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang +10 more
wiley +1 more source
Revista de Historia, 2020 Definimos cuatro características centrales de la economía política peruana en la era del desarrollismo: la secuencia de bonanzas exportadoras de diversas materias primas que limitaba la demanda por política industrial; la histórica debilidad estatal, en ...
José Carlos Orihuela
doaj
Advanced Science, EarlyView.The severity of acute pancreatitis (AP) is linked to reduced abundance of Bifidobacterium pseudolongum (B. pseudolongum). Administration of B. pseudolongum or its key metabolite acetate alleviates pancreatic and systemic inflammation by suppressing M1 macrophage polarization.
Langyi Guan +16 more
wiley +1 more source
, 2009 Recull de dades relacionades amb la biografia, la formació i pràctica professional, i la militància política i sindical en temps de la República i de l’Exili de Joan Costa ...
openaire +2 more sources
Letter from Geraldine Ferraro to the Red Cross of San Juan de Dios in Costa Rica [PDF]
, 1984 Letter from Geraldine Ferraro to the Red Cross of San Juan de Dios in Costa Rica. Letter has handwritten notes.https://ir.lawnet.fordham.edu/vice_presidential_campaign_correspondence_1984_international/1342/thumbnail ...
Ferraro, Geraldine +1 more
core +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Advanced Science, EarlyView.Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Revolutionizing Lithium Metal Anodes With 3D‐Printed Topology‐Optimized Hosts for Enhanced Stability
Advanced Science, EarlyView.This study presents a topology‐optimized lithium metal anode host fabricated via digital light processing (DLP) 3D printing. The reinforced microstructure provides mechanical stability, suppresses dendrite growth, and accommodates volume changes.
Xin Hu +5 more
wiley +1 more source
Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction
Advanced Science, EarlyView.We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang +9 more
wiley +1 more source
How Strong is the Case for Dollarization in Costa Rica? A Note on the Business Cycle Comovements with the United States [PDF]
We evaluate the proposal for official dollarization in Costa Rica by applying a new approach to measure the business cycle comovements with the United States. While the literature often focuses on the correlation of shocks, we point out that the response
Frank Westermann, Nannette Lindenberg
core +3 more sources
LAS PLANTAS EN EL BOSQUE DE MANGLE
Tecnociencia, 2006 El manglar es un ecosistema con pocas especies arbóreas, adaptadas a habitar en zonas inundadas periódicamente por las mareas. Las géneros presentes en la actualidad se originaron durante el Eoceno en la región Indo – Malaya (Rhizophora y Avicennia)
Jorge A. Mendieta B.
doaj