Results 281 to 290 of about 15,086 (322)

Nanomaterial‐Integrated 3D Biofabricated Structures for Advanced Biomedical Applications

Macromolecular Materials and Engineering, EarlyView.
This review investigates the integration of nanomaterials into 3D biofabricated structures, highlighting the potential in tissue regeneration, wound healing, and cancer therapy. It discusses key techniques, including bioprinting and electrospinning, while addressing challenges such as biocompatibility, scalability, and regulatory barriers.
Mustafijur Rahman, Tanvir Mahady Dip, Md Golam Nur, Md Hasibul Hossain, Finn Snow, Nusrat Binta Hossain, Azadeh Mirabedini, Anita Quigley, Rajiv Padhye, Shadi Houshyar   +9 more
wiley   +1 more source

Biomedical Applications of 3D‐Printed Polyamide: A Systematic Review

Macromolecular Materials and Engineering, EarlyView.
Additive manufacturing expands possibilities for personalized biomedical solutions, emphasizing the role of material science. This review examines the mechanical properties of 3D printed polyamide and explores its advantages and limitations in biomedical applications, including personalized implants, medical devices, and patient‐specific tools, as well,
Emese Paari‐Molnar, Wa'el Nafith Abdel‐Fattah Qa'dan, Kinga Kardos, Roland Told, Nitin Sahai, Peter Varga, Szilard Rendeki, Gabor Szabo, Kata Fekete, Tihamer Molnar, Adam Tibor Schlegl, Peter Maroti, Luca Toth   +12 more
wiley   +1 more source

Electrospun Poly (Glycerol Sebacate) (PGS) Membranes for Corneal Tissue Engineering

Macromolecular Materials and Engineering, EarlyView.
Fibrous PGS membranes that are composed of homogenous fibers are fabricated by electrospinning. Durability and permeability of the membranes closely resemble the natural cornea. Thereby, successfully supporting the proliferation of human corneal epithelial cells (HCEC) and human corneal endothelial cells (HCEndC).
Sumeyye Narin, Sevilay Burcu Sahin, Ebru Demir, Sibel Cetinel   +3 more
wiley   +1 more source

Design, Fabrication, and Evaluation of Hybrid Polycaprolactone/Graphene Scaffold Based on Additive Manufacturing and Electrospinning

Macromolecular Materials and Engineering, EarlyView.
A multi‐scale and multi‐material PCL/graphene scaffold was successfully fabricated by integrating extrusion‐based AM and solution electrospinning. The process was optimized using an image‐based method, achieving 87% fiber alignment with the intended orientation.
M. Tugrul Ucan, Duo Meng, Enes Aslan, Guilherme F. Caetano, Yanhao Hou, Weiguang Wang   +5 more
wiley   +1 more source

Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis

Med Research, EarlyView.
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang, Yanyun Pang, Peijia Zhu, Zhengdong Zhang, Sen Guo, Zhijian Wei, Wenzhao Wang, Bin Ning   +7 more
wiley   +1 more source

Effective Macroscopic Equations for Biological Fluid and Nutrients' Transport in Vascularized Tumors Growing Via Proliferation and Chemotaxis

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT This paper presents a system of partial differential equations designed to model fluid and nutrient transport within the growing tumor microenvironment. The fluid phase, representing both cells and extracellular fluids flowing within the interstitial space, is assumed to be intrinsically incompressible, so that growth can be modeled as a ...
Francesca Ballatore, Chiara Giverso, Raimondo Penta   +2 more
wiley   +1 more source

Integrating Nanotechnology With 3D Printing for Drug Delivery: Bone Regeneration and Beyond

Nano Select, EarlyView.
What happens when nanotechnology meets 3D printing? This review explores how their fusion transforms drug delivery and bone regeneration, creating smarter, more adaptable therapies. From nanomaterials to futuristic fabrication methods, the article maps innovations that could redefine personalized medicine and hints at the challenges researchers must ...
Felipe Sousa Siqueira, Anderson de Jesus Gomes, Claure Nain Lunardi   +2 more
wiley   +1 more source

The Design and Development of a Dexamethasone‐Tranfersome‐PF‐127/HA Stimuli‐Responsive Hydrogel for Intra‐Articular Therapy in Osteoarthritis

Nano Select, EarlyView.
A dexamethasone‐loaded transfersome‐based hydrogel was developed for sustained intra‐articular delivery in osteoarthritis. The system showed nanoscale particles size, high drug loading capacity, and shear‐thinning behavior. It enabled smooth injection, self‐healing, and prolonged drug release for up to 6 weeks.
Atang Motaung, Thankhoe A. Rants'o, Ravindra V. Badhe, Khonzisizwe Somandi, Yahya E. Choonara   +4 more
wiley   +1 more source

A geriatrician's approach to managing the complex older adult with obesity

Obesity, EarlyView.
Abstract The prevalence of obesity in older adults is rapidly increasing due to the demographic shift occurring globally. Older adults with obesity face health care challenges due to multimorbidity, functional dependency, and disability. This population often has prior history of struggles through weight‐loss attempts during the middle years of life ...
Shenbagam Dewar
wiley   +1 more source