Results 81 to 90 of about 15,086 (322)
Rolling Ultrasharp Microneedle Spheres Enable Topical Delivery of Biologics Through the Skin
Rolling ultraminiaturized microneedle spheres (RUMS), created via two‐photon polymerization, unlock effective and painless topical delivery of messenger RNA (mRNA) and drugs through the skin. By gently forming thousands of microscopic pores, RUMS boost skin permeability by up to 100‐fold.
Theocharis Nikiforos Iordanidis+6 more
wiley +1 more source
The repair of chondral injuries is a very important problem and a subject of many experimental and clinical studies. Different techniques to induce articular cartilage repair are under investigation. In the present study, we have investigated whether the
Janusz Popko+3 more
doaj +1 more source
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi+10 more
wiley +1 more source
A 70-year-old woman with a hoarse voice and dry cough was referred to our hospital. Positron emission tomography/computed tomography showed abnormal accumulation of fluorine-18 fluorodeoxyglucose (FDG) at the nasal septum, larynx, trachea, bronchus, and ...
Hirokazu Tokuyasu+8 more
doaj
Correction of severe columella and tip retraction in silicone implanted Asian short noses. [PDF]
BACKGROUND: Silicone Implants and other alloplastic materials are frequently used in rhinoplasty to augment Asian short noses. However, nasal deformities as a result of implant-related infections are increasing in incidence.
Pasche, P.+2 more
core +1 more source
Ultra‐Tiny Gelatin Nanoparticles‐Assisted 3D Stem Cell Spheroids for Engineering Tissue Regeneration
GNPs effectively guide the formation of structurally compact and functionally enhanced stem cell spheroids. This GNP‐assisted 3D culture system improves cell–cell and cell‐ECM interactions, leading to superior viability and complexity. Time‐dependent regenerative potential is demonstrated in both bone and skin defects, positioning GNP‐spheroids as a ...
Dream Kim+7 more
wiley +1 more source
New strategies for base frame fabrication in microtia reconstruction
The base frame provides a stable support for the helix, antihelix, and tragus–antitragus complex in microtia reconstruction, and this support is vital to attain a highly defined outline for a reconstructed auricle.
Yiyuan Li+6 more
doaj +1 more source
Chest wall reconstruction following a speedboat propeller injury [PDF]
Propeller blade injuries to the chest are uncommon but can result in devastating injuries. We describe a case of a 44 year-old male scuba diver who was dragged by sea currents into the propeller of a speedboat. He suffered extensive chest wall trauma but
Casha, Aaron+2 more
core
Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley +1 more source
Biomechanical Characterisation of the Human Auricular Cartilages; Implications for Tissue Engineering [PDF]
Currently, autologous cartilage provides the gold standard for auricular reconstruction. However, synthetic biomaterials offer a number of advantages for ear reconstruction including decreased donor site morbidity and earlier surgery. Critical to implant
Butler, PE+4 more
core +1 more source