Results 121 to 130 of about 4,509,666 (343)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Educational Costs of Residents in a Teaching Hospital: a case study

پژوهش‌های سلامت‌محور, 2019
Educational Costs of Residents in a Teaching Hospital: a case study   Aleboyeh Mahmoud Reza1, Reza pour Aziz2, Meshkani Zahra3*, Alipour Vahid4,  Soleimani movahed Maryam4   1. Associate Professor, Department of Anesthesiology, Faculty of Medicine, Iran
Mahmoud Reza Aleboyeh, Aziz Reza pour, Zahra Meshkani, Vahid Alipour, Maryam Soleimani movahed   +4 more
doaj  

Transfer Effects in Task-Set Cost and Dual-Task Cost After Dual-Task Training in Older and Younger Adults: Further Evidence for Cognitive Plasticity in Attentional Control in Late Adulthood

, 2008
Louis Bherer, Arthur F. Kramer, Matthew S. Peterson, Stanley J. Colcombe, Kirk I. Erickson, Ensar Becic   +5 more
openalex   +1 more source

INVO: a simple, low cost effective assisted reproductive technology [PDF]

, 2008
R. Frydman, Claude Ranoux
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Fabrication of Low-Cost Paper-Based Microfluidic Devices by Embossing or Cut-and-Stack Methods

, 2014
Martin Thuo, Ramsés V. Martínez, W.H. Lan, Xinyu Liu, Jabulani R. Barber, Manza B. J. Atkinson, Dineth Bandarage, Jean‐Francis Bloch, George M. Whitesides   +8 more
openalex   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Dynamics modeling of multicomponent metal ions’ removal onto low-cost buckwheat hulls [PDF]

, 2020
E. Tomczak, W. Kamiński
openalex   +1 more source

Cost-effectiveness of first line nivolumab-ipilimumab combination therapy for advanced non-small cell lung cancer: A systematic review and methodological quality assessment [PDF]

, 2023
Remziye Zaim, Ken Redekop, Carin A. Uyl‐de Groot   +2 more
openalex   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source