Results 121 to 130 of about 47,260 (268)

Cost-utility analysis of robotic and conventional total knee arthroplasty: A 200-patient micro-costing study in a public sector institution. [PDF]

J Robot Surg
Wignadasan W, Fontalis A, Alsheddi A, Tahmassebi J, Patel N, Pizzo E, Haddad FS.   +6 more
europepmc   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

The WHO costing and budgeting tool for national action plans on antimicrobial resistance-a review and assessment of impact in Africa. [PDF]

JAC Antimicrob Resist
Mazengiya YD, Gahimbare L, Judith A, Patriarchi A, Verboom P, Fuller W, Ahmed YA.   +6 more
europepmc   +1 more source

What are the “costs” of cost-effectiveness? [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2018
openaire   +2 more sources

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Costing of AMR can Incentivize Responses to One Health. [PDF]

Ann Glob Health
Kumar P.
europepmc   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Climate change and health system preparedness: A scoping review of adaptation plans in Central America and the Caribbean. [PDF]

Lancet Reg Health Am
Bonilla-Zarrazaga L, Arriaga A, Castro-Vargas S, Boue J, Bauhoff S, Aguilar-Rivera AM, Gongora-Salazar P, Fahr P.   +7 more
europepmc   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S. Sperber, Tanja Schmitz‐Hübsch, Frederike C. Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne‐Katrin Pröbstel, Xiao‐Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul   +19 more
wiley   +1 more source

What Does "Success" Mean in the Cost-Effectiveness of Fetal Fibronectin Testing? [Response to Letter]. [PDF]

Clinicoecon Outcomes Res
Abushanab D, Al-Dewik N, AlNasr R, Alenany R, Kattan L, Alali G, Al-Naama A, Al-Hail M, Farrell T, Mohammed HRK, Elkassem W, Pallivalapila A, Thomas B, Al-Badriyeh D.   +13 more
europepmc   +1 more source