Results 71 to 80 of about 349,665 (299)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

An exploration of the factors affecting the diffusion of advanced costing techniques: a comparative analysis of two surveys (1996-2005) [PDF]

open access: yes
The issue of cost calculation has been largely debated in the last years under the pressure of the perceived lost of relevance of the so called "traditional cost accounting approaches".
Alessandro Marelli   +3 more
core   +3 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Enhancing Cucumber Production Sustainability by Incorporated Pest Management: A Comparative Evaluation of Cost and Profitability [PDF]

open access: yesE3S Web of Conferences
This research investigates the efficacy of integrated Pest management (IPM) techniques in cucumber cultivation, focusing at the utilization of natural control strategies to reduce pest-associated losses and improve crop productivity.
Shankar Raman Ravi   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Strategies for implementing activity-based costing in the UK manufacturing industry [PDF]

open access: yes, 2013
The purpose of this paper is to report the findings with a case study on why activity based costing lacks impact in the UK manufacturing industry. Activity based costing was performed on selected MT range subsystems of an electrical power generator to ...
Cheung, Wai   +3 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

UTILITY OF THE METHOD T.H.M. (MACHINE - HOUR - RATE) PRODUCTION CENTURY PROCESS AUTOMATION [PDF]

open access: yesStrategii Manageriale, 2014
The method T.H.M. (machine - hour - rate) gives greater accuracy in the factories or departments, where production is largely by machinery. In the specialty literature, the notion of price - the time - the car is defined as "œa rate calculated by ...
Cristina-Otilia, ȚENOVICI
doaj  

Accounting and Auditing of Costs and Costing of Military Products during Martial Law and Post-War Reconstruction: Institutional Aspect [PDF]

open access: yesОблік і фінанси
The war in Ukraine has revived the discussion on the institutionalization of accounting and auditing and the social and political nature of accounting data generated by the accounting system of an enterprise.
Viktoria Yatsenko
doaj   +1 more source

METHOD TIME DRIVEN ACTIVITY BASED COSTING – LITERATURE REVIEW [PDF]

open access: yes
This article presents a literature review of the method Time Driven Activity Based Costing, like an instrument to better assignment of costs to activities and their comparison with antecedent method Activity Based Costing.
Oleg DEJNEGA
core  

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