Results 71 to 80 of about 111,455 (252)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Vendor selection and evaluation : an activity based costing appoach. [PDF]

open access: yes
In this paper we propose an Activity Based Costing approach for vendor selection and evaluation. This system allows us to compute total costs caused by a supplier in a firm's production process, thereby increasing the objectivity in the selection process.
Konings, Joep, Roodhooft, Filip
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Target Costing: um perfil das publicações entre os anos de 2000 a 2005 [PDF]

open access: yes, 2006
TCC (Graduação) - Universidade Federal de Santa Catarina. Centro Socioeconômico. Curso de Ciências ContábeisEste trabalho visa traçar um perfil das publicações sobre Target Costing divulgadas nos principais periódicos, de Contabilidade e Administração ...
Shimabukuro, Karina Mitiko
core  

Pengoptimalan Strategi Harga Dalam Industri Gula Aren: Pendekatan Process Costing [PDF]

open access: yes
Perhitungan cost of goods manufacture penting dalam penentuan harga jual produk. Sayangnya, masih terdapat beberapa pemilik usaha belum mengimplementasikan metode tersebut sehingga berdampak pada tidak optimalnya laba yang diperoleh. Studi deskriptif ini
Rahmanto, Basuki Toto   +5 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Cost of diabetes in type II diabetic patients

open access: yesPayesh, 2012
Objective (s): To determine economics cost of diabetes in type II diabetic patients under the cover of Naderkazemi clinic in Shiraz in the first half of 2008.Methods: this study is an applicable one and the way of study is descriptive-analytic.the study ...
Aboozar Sadeghi Mazidi   +4 more
doaj  

THE CONCEPT OF MANAGEMENT ACCOUNTING BASED ON PRODUCT MOVEMENT AND COST INCREASE IN CONTROLLING SYSTEM

open access: yesУчёт. Анализ. Аудит, 2019
The article describes the main features of the management accounting concept based on the product movement at different stages of the manufacturing process by cost centers.
TATYANA Karpova
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

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