Results 11 to 20 of about 25,689 (170)

Assessment of smoking status based on cotinine levels in nasal lavage fluid [PDF]

Tobacco Induced Diseases, 2009
Cotinine is a principal metabolite of nicotine with a substantially longer half-life, and cotinine levels in saliva, urine or serum are widely used to validate self-reported smoking status.
Mehmet Hakan Ozdener, Karen K Yee, Ryan McDermott, Beverly J Cowart, Aldona A Vainius, Pamela Dalton, Nancy E Rawson   +6 more
doaj   +2 more sources

Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure. [PDF]

, 2012
: Background Two single-nucleotide polymorphisms, rs1051730 and rs16969968, located within the nicotinic acetylcholine receptor gene cluster on chromosome 15q25 locus, are associated with heaviness of smoking, risk for lung cancer, and other smoking ...
Morris, RW, Timpson, NJ, Whincup, PH, Uhl, GR, Sattar, N, Ebrahim, S, Brennan, P, Hingorani, AD, Johnson, PC, Upton, MN, EPIC Study Group, Davey Smith, G, Jefferis, BJ, Timofeeva, MN, Riboli, E, Aveyard, P, Prieto-Merino, D, Amuzu, A, Munafò, MR, Palmer, TM, Relton, C, Vineis, P, Watt, G, Casas, JP, Padmanabhan, S, Johnstone, EC, Walther, D   +26 more
core   +6 more sources

Relation of Serum Cotinine with Passive Smoking

Pakistan Journal of Medicine and Dentistry
Background: Cotinine is a major metabolite of nicotine and retains for a substantial time in different body fluids. It is considered as a passive smoke exposure marker. Studies on different biochemical markers of tobacco smoke exposure are lacking in
Zil-a-Rubab, Mohammad Ata-ur-Rehman, Saeeda Baig   +2 more
doaj   +1 more source

Cotinine-assessed second-hand smoke exposure and risk of cardiovascular disease in older adults [PDF]

, 2010
Objectives: To examine whether second-hand smoke (SHS) exposure measured by serum cotinine is associated with increased coronary heart disease (CHD) and stroke risk among contemporary older British adults.
Jefferis, BJ, Lawlor, DA, Feyerabend, C, Whincup, PH, Doig, M, Cook, DG, Ebrahim, S, Wannamethee, SG, McMeekin, L   +8 more
core   +1 more source

Nicotine and its metabolite cotinine target MD2 and inhibit TLR4 signaling

The Innovation, 2021
Nicotine is the principal alkaloid of tobacco often manufactured into cigarettes and belongs to a highly addictive class of drugs. Nicotine attenuates the neuroinflammation induced by microglial activation.
Hongyuan Li, Yinghua Peng, Cong Lin, Xiaozheng Zhang, Tianshu Zhang, Yibo Wang, Yuanpeng Li, Siru Wu, Hongshuang Wang, Mark R. Hutchinson, Linda R. Watkins, Xiaohui Wang   +11 more
doaj   +1 more source

Changes in environmental tobacco smoke exposure over a 20-year period: Cross-sectional and longitudinal analyses [PDF]

, 2008
AIMS:  To examine long‐term changes in environmental tobacco smoke (ETS) exposure in British men between 1978 and 2000, using serum cotinine. DESIGN:  Prospective cohort: British Regional Heart Study.
Jefferis, BJ, Feyerabend, C, Whincup, PH, Doig, M, Cook, DG, Lennon, LT, McMeekin, L, Wannamethee, SG, Thomson, AG   +8 more
core   +1 more source

Salivary nicotine and cotinine concentrations in unstimulated and stimulated saliva [PDF]

, 2010
Salivary nicotine and salivary cotinine is widely used in clinical and epidemiological studies to validate smoking cessation. However, the reported collection for salivary nicotine and salivary cotinine vary by technique and duration.
Bond, A. J., Wolff, K.; id_orcid, Robson, N.   +2 more
core   +7 more sources

Secondhand smoke (SHS) exposure is associated with circulating markers of inflammation and endothelial function in adult men and women [PDF]

, 2009
AIMS: Secondhand smoke (SHS) exposure is associated with elevated CHD risks. Yet the pathways through which this may operate have not been investigated in epidemiologic studies with objective SHS exposure measures and a wide range of CHD risk factors ...
Lowe, G.D.O., Welsh, P, Lowe, GDO, Jefferis, B. J., Whincup, PH, Whincup, P.H., Ebrahim, S, Wannamethee, S.G., Jefferis, B.J., Lawlor, D. A., Rumley, A., McMeekin, L., Ebrahim, S., Whincup, P. H., Cook, D. G., Wannamethee, SG, Jefferis, BJ, Welsh, P., Lowe, GD, Feyerabend, C, Wannamethee, S. G., Lowe, G. D. O., Whincup, P., Feyerabend, C., Doig, M., Lawlor, DA, Cook, D.G., Carson, C., Doig, M, Rumley, A, Cook, DG, Carson, C, McMeekin, L, Lawlor, D.A.   +33 more
core   +1 more source

Relapse to smoking during unaided cessation: clinical, cognitive and motivational predictors [PDF]

, 2010
Rationale: Neurobiological models of addiction suggest that abnormalities of brain reward circuitry distort salience attribution and inhibitory control processes, which in turn contribute to high relapse rates.
Jane Powell, John Powell, Powell, Jane, Powell, John, Lynne Dawkins, Alan Pickering, West, Robert, Robert West, Dawkins, Lynne, Powell, John; id_orcid, Powell, Jane H., Pickering, Alan, Powell, J.H., Powell, J.F., Pickering, A., West, R., Dawkins, L.   +16 more
core   +1 more source

Prenatal Cotinine Levels and ADHD Among Offspring [PDF]

, 2022
OBJECTIVES: An association between maternal smoking during pregnancy and offspring attention-deficit/hyperactivity disorder (ADHD) has been shown across several studies based on self-reports.
Sourander A, Brown AS, Cheslack-Postava K, Hinkka-Yli-Salomäki S, Surcel HM, Gyllenberg D, Sucksdorff M, Chudal R   +7 more
core   +3 more sources