Results 271 to 280 of about 62,786 (347)

Sodium-Glucose Cotransporter-2 Inhibitors and Arrhythmias: A Meta-Analysis of 38 Randomized Controlled Trials. [PDF]

open access: yesJACC Adv
Jaiswal V   +10 more
europepmc   +1 more source

Computational Drug Repositioning in Cardiorenal Disease: Opportunities, Challenges, and Approaches

open access: yes
PROTEOMICS, EarlyView.
Paul Perco   +7 more
wiley   +1 more source

Ibuprofen inhibits human sweet taste and glucose detection implicating an additional mechanism of metabolic disease risk reduction

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The human sweet taste receptor, TAS1R2–TAS1R3, conveys sweet taste in the mouth and may help regulate glucose metabolism throughout the body. Ibuprofen and naproxen are structurally similar to known inhibitors of TAS1R2–TAS1R3 and have been associated with metabolic benefits.
Emily C. Hanselman   +6 more
wiley   +1 more source

Obesity‐related glomerulopathy: How it happens and future perspectives

open access: yesDiabetic Medicine, EarlyView.
Abstract Obesity‐related glomerulopathy (ORG) is an emerging complication of excess adiposity. Its incidence rises alongside the obesity pandemic. Up to 40% of individuals can be affected by ORG, irrespective of the status of glomerular filtration rate and albuminuria.
Jian‐Wen Samuel Lee‐Boey   +7 more
wiley   +1 more source

The cardio‐renal‐metabolic role of the nod‐like receptor protein‐3 and senescence‐associated secretory phenotype in early sodium/glucose cotransporter‐2 inhibitor therapy in people with diabetes who have had a myocardial infarction

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims Following an acute myocardial infarction (AMI), individuals with type 2 diabetes (T2DM) have a 2‐to‐3 fold increased risk of mortality compared to those without diabetes, and globally cardiorenal complications account for 50% of diabetes‐related deaths.
M. U. Shah   +4 more
wiley   +1 more source

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