Results 91 to 100 of about 268,281 (297)

Mitochondrial Localization of Cx26 Promotes Colorectal Cancer Malignancy and Exposes a Fatal Vulnerability to Drug Targeting

open access: yesAdvanced Science, EarlyView.
Mitochondrial localization of Cx26 emerges as a double‐edged sword in colorectal cancer. PIMT‐mediated methylation of Cx26 promotes its mitochondrial localization and stability. Mitochondrial Cx26 then facilitates ER‐mitochondria communication and Ca2+ signaling, thereby promoting metastatic progression. Bortezomib exploits this malignant adaptation by
Jie Wang   +9 more
wiley   +1 more source

Transgenic and histological approaches to investigating the development of the stalk-eyed fly, Teleopsis dalmanni [PDF]

open access: yes, 2009
Stalk-eyed flies of the family Diopsidae have their eyes laterally displaced on the end of head extensions called “eye-stalks”. Diopsids vary in their degree of sexual dimorphism for eyespan (distance between the eyes).
Warren, I.A.
core  

Wafer‐Scale Dendritic Nanoporous Platinum Films for Neural Electrodes

open access: yesAdvanced Science, EarlyView.
Wafer‐scale dendritic nanoporous platinum films with intrinsic nanoscale porosity are synthesized by suraface‐confined wet chemistry and transferred onto flexible substrates to create tissue‐conformal neural electrodes. The ultrathin films combine mechanical flexibility with electrochemical stability, enabling low‐impedance, high‐capacitance interfaces
Kyeongbin Kang   +14 more
wiley   +1 more source

Cotton Stalk

open access: yes
Image of a cotton stalk with cotton boles and ...
Mauzey, Merritt T. (Merritt Thomas), 1898-1973
core  

Dual‐Dynamically Crosslinked Nanogels Enable Prolonged Ocular Retention for Multimodal Dry Eye Therapy

open access: yesAdvanced Science, EarlyView.
This berberine‐loaded dual‐dynamically crosslinked nanogel integrates tannic acid‐zinc metal‐phenolic networks and carboxymethyl chitosan/aldehyde‐functionalized poly(ethylene glycol) dynamic Schiff base networks, achieving 1‐year colloidal and antioxidant stability, sustained corneal berberine exposure for 24 h to support convenient once‐daily dosing,
Yanru Xin   +7 more
wiley   +1 more source

Cotton Stalk Puller.

open access: yes, 1881
Patent for a new and improved cotton stalk puller. This design utilizes "[a] pulling-wheel having radial jaws that are opened and closed by cam devices" when "[i]t is driven astride the [cotton] row, and will be found to operate rapidly and with absolute
Wilson, John C.
core  

Aged ZnO Nanoparticles Promote Breast Cancer Lung Metastasis by Remodeling the Pulmonary Microenvironment Through the CXCL10/Wnt/β‐Catenin Axis

open access: yesAdvanced Science, EarlyView.
In summary, pulmonary exposure to ZnO NPs, particularly aged NPs, promotes breast cancer metastasis by remodelling the lung tumour microenvironment. Aged ZnO NPs enrich M2‐macrophages, MDSCs and activated CAFs to form an immunosuppressive metastatic niche. CXCL10 from these cells drives metastasis via Wnt/β‐catenin activation.
Yong Zhu   +8 more
wiley   +1 more source

Design and Experiment of a Vertical Cotton Stalk Crushing and Returning Machine with Large and Small Dual-Blade Discs

open access: yesAgriculture
To address the problems of low crushing efficiency and uneven distribution in traditional straw crushing and returning machines for cotton stalk return operations in Xinjiang, a vertical straw crushing and returning machine with large and small dual ...
Xiaohu Guo   +6 more
doaj   +1 more source

Cotton-Stalk Cutter

open access: yes, 1913
Patent for a more efficient and simple cotton stalk chopper with the ability for the chopping drum to be moved up and down in the on and off ...
Thomsen, John
core  

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