Results 101 to 110 of about 94,849 (289)

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

A PILOT STUDY FOR THE USE OF COUMARIN-480 TO ENHANCE FINGERMARKS

Studia Universitatis Babes-Bolyai Chemia, 2019
A new alternative super glue post-treatment method for the enhancement of fingermarks over two different non-porous surfaces including glass slides and high-density polyethylene (HDPE) sheets have been investigated.
Muhammad YASEEN, Nouman RASOOL, Zahid FAROOQ, Shahbaz NAZIR, Shumaila CHOHAN   +4 more
doaj   +1 more source

New coumarin-[60] fullerene dyads connected by an alkynyl linkage: Synthesis and fluorescence studies. Evidence for efficient singlet-singlet energy transfer [PDF]

, 2015
Two new coumarin-[60] fullerene dyads, in which an alkyne group covalently links C60 to coumarin, are synthesized via 1,3-dipolar cycloaddition and spectroscopically characterized.
Berberan-Santos, Mário N., Brites, Maria João, Fedorov, Alexander, Nascimento, Susana   +3 more
core   +1 more source

Pharmacokinetic Evaluation of a Cinnamon Product on CYP2A6 Substrate Drugs: Application of a Novel Tool Involving the Nicotine Metabolite Ratio

Clinical Pharmacology &Therapeutics, EarlyView.
Cinnamon (Cinnamomum spp.) is used as a culinary spice and dietary supplement. A major constituent, cinnamaldehyde, was previously shown to inactivate cytochrome P450 (CYP) 2A6 in vitro. A mechanistic static model predicted an ~5‐fold increase in the AUC of the CYP2A6 substrates nicotine and letrozole.
Aiden‐Hung P. Nguyen, Deena L. Hadi, Daniel A. Todd, Preston K. Manwill, John R. White, Matthew E. Layton, Nadja B. Cech, Kenneth E. Thummel, Mary F. Paine   +8 more
wiley   +1 more source

Phenotypic, molecular, and in silico characterization of coumarin as carbapenemase inhibitor to fight carbapenem-resistant Klebsiella pneumoniae

BMC Microbiology
Background Carbapenems represent the first line treatment of serious infections caused by drug-resistant Klebsiella pneumoniae. Carbapenem-resistant K. pneumoniae (CRKP) is one of the urgent threats to human health worldwide.
Mahmoud Saad Abdel-Halim, Amira M. El-Ganiny, Basem Mansour, Galal Yahya, Hemat K. Abd El Latif, Momen Askoura   +5 more
doaj   +1 more source

Dual‐Stabilized Single‐Site Fe(II) for Catalytic Conversion of CO2 to Propiolic Acid Under Ambient Condition

EcoEnergy, EarlyView.
We develop a highly cost‐effective heterogeneous catalyst for efficient CO2 conversion to propiolic acid under mild conditions via a nano‐confined approach with porous MIL support. ABSTRACT Efficient conversion of carbon dioxide to organics has been a promising outlet for value‐added carbon dioxide consumption.
Bin Lei, Zhenzhen Zhou, Xiao Liu, Bo Li, Wenyuan Wang, Jian‐Gong Ma, Peng Cheng   +6 more
wiley   +1 more source

Coumarin-Induced Delay of Rice Seed Germination Is Mediated by Suppression of Abscisic Acid Catabolism and Reactive Oxygen Species Production

Frontiers in Plant Science, 2019
Abscisic acid (ABA) is a crucial phytohormone for the regulation of seed germination. The ABA content of seeds is regulated by synthesis and catabolic pathways.
Bing-Xian Chen, Yuan-Xuan Peng, Yuan-Xuan Peng, Jia-Dong Gao, Qi Zhang, Qin-Jian Liu, Hua Fu, Jun Liu   +7 more
doaj   +1 more source

MELD score predicts outcomes in patients with advanced heart failure: A longitudinal evaluation

ESC Heart Failure, Volume 12, Issue 2, Page 839-847, April 2025.
Abstract Aims Advanced heart failure (AHF) is characterized by recurrent episodes of haemodynamic instability and frequent hospitalizations, leading to a progressive decline in quality of life and high mortality rates. The objectives of this study were to evaluate the effect of the model for end‐stage liver disease (MELD) score and its variations in ...
Francesco Curcio, Cristiano Amarelli, Rosaria Chiappetti, Irene Mattucci, Veronica Flocco, Mahmoud Issa Rammal, Ciro Abete, Francesca Mazzella, Ciro Maiello, Pasquale Abete, Francesco Cacciatore   +10 more
wiley   +1 more source

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

European Journal of Organic Chemistry, EarlyView.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

The Arabidopsis NPF7.2 mediates coumarin uptake for root iron acquisition. [PDF]

New Phytol
Summary Iron (Fe) is a transition metal necessary for achieving essential physiological processes throughout the plant lifecycle. In Arabidopsis thaliana, secreting Fe‐mobilizing coumarins (FMC) is a key mechanism enabling roots to acquire nonbioavailable Fe present in soils.
Watanabe S, Li M, Rossille A, Boustani C, Robe K, Kanno Y, Seo M, Dubos C.   +7 more
europepmc   +2 more sources