Results 121 to 130 of about 6,128,347 (311)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

A study of A8 and A2 migrants in Nottingham [PDF]

open access: yes, 2009
The research was commissioned by Nottingham City Council and One Nottingham in August 2008 and was conducted by a team of researchers from the Salford Housing & Urban Studies Unit at the University of Salford.
Morris, G, Scullion, L, Steele, A
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

2012 Grantmakers Information Technology Survey Report [PDF]

open access: yes, 2012
Together the Technology Affinity Group (TAG) and Grants Managers Network (GMN) conducted an information technology survey of grantmaking organizations in July 2012.
Lisa Pool
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Some are more equal than others: responses to political violence [PDF]

open access: yes, 2014
While it is true that the US has, for once, signed up to a UN Security Council statement which calls for an "immediate and unconditional humanitarian cease-fire”, this might still be considered a tactical step to prevent more strongly worded resolutions ...
Head, Naomi
core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

La tipología de las entidades locales y las fórmulas institucionales de intermunicipalidad

open access: yesRevista Vasca de Administración Pública, 2017
In this study the different types of local entities mentioned in the recent Act on Local Entities of Euskadi are associated and analyzed. Thus, we deep into the study of the Basque municipalities, councils from Alava, municipal associations, the ...
Francisco Javier Enériz Olaechea
doaj   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo   +12 more
wiley   +1 more source

Council Business [PDF]

open access: yesThe Journal of the American Pharmaceutical Association (1912), 1913
openaire   +1 more source

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