Results 121 to 130 of about 3,313,431 (294)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

EDITORIAL: Jordanian Nursing Council: A National Regulatory Institution

open access: yesJordan Journal of Nursing Research
The Jordanian Nursing Council (JNC) has made significant strides in advancing the nursing and midwifery professions in Jordan. Through its robust regulatory framework, strategic partnerships, and commitment to continuous professional development, the JNC
Hani Nawafleh
doaj  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Other title: January, March, May Council meetings, progress report

open access: yes, 1960
"June 1960."JANUARY - MAY MEETINGS -- COUNCIL ACTION ON PROPOSALS -- Carry-over of Losses Under Kansas Income Tax - Proposal No. 16 -- Status of Council Work -- COMMITTEE ACTIVITY AND REPORTS -- Agriculture and Livestock -- Noxious Weeds -Proposal No. 31
Kansas. Legislature. Legislative Council.
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Namık Kemal’de Devletin Niteliği ve Temel Dayanakları

open access: yesAkademik İncelemeler Dergisi, 2014
Namık Kemal Yeni Osmanlı düşüncesinin en önemli isimlerinden biridir. Namık Kemal hem kendi döneminin entelektüel gündemine hem de kendinden sonraki dönemlerin entelektüel gündemlerine önemli katkılarda bulunmuştur. Birçok konuda öncü nitelikli fikirleri
Kenan Çağan
doaj  

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Other title: September Council meeting, progress report

open access: yes, 1957
"September 1957."SEPTEMBER COUNCIL MEETING -- Status of Council Work -- New Proposals Introduced -- Legislative Committee on Economy and Efficiency - First Interim Report -- COUNCIL ACTION ON PROPOSALS -- Oil Transportation and Marketing - Pro. No. 11 --
Kansas Legislature. Legislative Council.
core   +1 more source

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